<body><div><figure><img src="https://img.particlenews.com/image.php?type=thumbnail_580x000&amp;url=0zUWvR_1GodUUuX00" alt="https://img.particlenews.com/image.php?url=0zUWvR_1GodUUuX00" width="788" height="443" ><figcaption>2 dead after wrong-way crash on I-64 in Frontenac</figcaption></figure>ST. LOUIS COUNTY, Mo. - Two people were killed in a three-vehicle wrong-way crash on Interstate 64 Wednesday night in Frontenac.According to the Missouri State Highway Patrol (MSHP), the crash occurred shortly after 9:30 p.m. on westbound I-64 east of N. Ballas Rd. It involved a Toyota FJ Cruiser, Nissan Altima and Hyundai Genesis.The Nissan was traveling the wrong way on westbound I-64 when it collided head-on with the Hyundai, MSHP said.According to MSHP, the impact pushed the Hyundai into the path of the Toyota, which then struck the backend of the vehicle.The driver of the Nissan, a 25-year-old from Marshall, Missouri, and the driver of the Hyundai, a 30-year-old St. Louis man, were both pronounced dead at the scene. No other injuries were reported, according to MSHP.All drivers involved were wearing a seatbelt at the time of the crash, MSHP said.Copyright 2026 Nexstar Media, Inc. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.For the latest news, weather, sports, and streaming video, head to FOX 2.</div></body>

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ST. LOUIS COUNTY, Mo. - Two people were killed in a three-vehicle wrong-way crash on Interstate 64 Wednesday night in Frontenac. According to the Missouri State Highway Patrol (MSHP), the crash occurred shortly after 9:30 p.m. on westbound I-64 east of N. Ballas Rd. It involved a Toyota FJ Cruiser, Nissan Altima and Hyundai Genesis.

2 dead after wrong-way crash on I-64 in Frontenac

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ST. LOUIS COUNTY, Mo. - Two people were killed in a three-vehicle wrong-way crash on Interstate 64 Wednesday night in Frontenac. According to the Missouri 

2 dead after wrong-way crash on I-64 in Frontenac

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