Indianapolis Colts at Dallas Cowboys odds, picks and predictions

Jess Root

Sportsbook Wire

After 2 home games in a row, the Indianapolis Colts (4-7-1) are on the road in Week 13 to take on the Dallas Cowboys (8-3) Sunday night in prime time. The game at AT&T Stadium in Arlington kicks off at 8:20 p.m. ET (NBC). Below, we analyze Tipico Sportsbook's lines around the Colts vs. Cowboys, and make our expert NFL picks and predictions.

The Colts won the coaching debut of Jeff Saturday 3 weeks ago with a 25-20 victory over the Las Vegas Raiders, but have dropped 2 straight games. They lost 24-17 to the Pittsburgh Steelers on Monday night as 2.5-point favorites after losing the week before 17-16 to the Philadelphia Eagles.

The Cowboys defeated the New York Giants 28-20 on Thanksgiving Day, but failed to cover the 10.5-point spread as favorites. They have a 2-game winning streak and have won 4 of their last 5 games.

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Colts at Cowboys odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:23 a.m. ET.

Moneyline (ML): Colts +400 (bet $100 to win $400) | Cowboys -500 (bet $500 to win $100)
Against the spread (ATS): Colts +10.5 (-113) | Cowboys -10.5 (-107)
Over/Under (O/U): 44 (O: -109 | U: -111)

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Colts at Cowboys key injuries

Colts

CB Kenny Moore II (ankle) out
CB Isaiah Rodgers (knee) questionable
OL Braden Smith (illness) out
TE Jelani Woods (shoulder, quad) questionable

Cowboys

LB Anthony Barr (hamstring) questionable
DT Quinton Bohanna (knee) questionable
CB Trevon Diggs (illness) questionable
WR Michael Gallup (illness) questionable
S Jayron Kearse (shoulder) questionable

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Colts at Cowboys picks and predictions

Prediction

Cowboys 27, Colts 13

Moneyline

The Cowboys are 5-1 at home this season and have won their last 5.

The Colts are 2-4 on the road, but their last win was on the road.

This is a game the Cowboys should win, even with potentially missing players with the flu bug. But with the moneyline what it is, PASS.

Against the spread

The Colts have lost by double digits only twice this season while the Cowboys have 5 double-digit wins out of their 8 this season.

The Colts have the most turnovers in the league (21) and the Cowboys are 8th in the league with 16 takeaways.

The Colts, averaging 15.8 points per game, are 20th in scoring. The Cowboys are No. 2 in points allowed at 17.0.

It appears unlikely the Colts will be able to even reach their season average, while the Cowboys have scored 28 or more in 4 straight games.

BET COWBOYS -10.5 (-113).

Over/Under

Only 3 of the Colts' 12 games have seen the Over hit. The Cowboys are 4-6-1 O/U on the season.

Only 1 of the Colts' last 6 games has had more than 44 total points.

BET UNDER 44 (-111).

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