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First look: Detroit Lions at New England Patriots odds and lines

The Detroit Lions (1-3) visit the New England Patriots (1-3) Sunday in an NFC vs. AFC matchup. Kickoff from Gillette Stadium is slated for 1 p.m. ET (FOX). Below, we look at the Lions vs. Patriots odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The Lions have dropped their last 2 games — against the Seattle Seahawks  (48-45) on Sunday and vs. the Minnesota Vikings (28-24). After a tough Week 1 loss to the Philadelphia Eagles (38-35), the Lions bounced back with a Week 2 win against the Washington Commanders (36-27).

Also seeAll Week 5 odds and lines

The Patriots have also lost their last 2 games — an overtime loss Sunday to the Green Bay Packers (27-24) and against the Baltimore Ravens (37-26). After an opening los to the Miami Dolphins (20-7), the Patriots got their only win of the season in Week 2 vs. the Pittsburgh Steelers (17-14).

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Lions at Patriots odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 12:31 a.m. ET.

  • Moneyline (ML): Lions +115 (bet $100 to win $115) | Patriots -130 (bet $135 to win $100)
  • Against the spread (ATS): Lions +2.5 (-107) | Patriots -2.5 (-115)
  • Over/Under (O/U): 47.5 (O: -110 | U: -110)

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2022 betting stats

  • ML: Lions 1-3 | Patriots 1-3
  • ATS: Lions 3-1 | Patriots 0-2-1
  • O/U: Lions 4-0 | Patriots 2-2

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Lions vs. Patriots head-to-head

Neither team has looked very good and the Patriots are especially not living up to expectations. The Lions offense is looking much improved, scoring 45 points vs. Seattle, but the Lions defense is allowing the most points per game in the league. The Patriots are missing starting QB Mac Jones, but the defense has looked pretty strong. If major Detroit playmakers in WR Amon-Ra St. Brown and RB D’Andre Swift are out again, I’m not sure that I would trust QB Jared Goff to overcome a very solid Patriots defense.

New England leads the all-time series 7-5, but Detroit won the last meeting in 2018 at home 26-10.

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