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New Orleans Saints at Carolina Panthers odds, picks and predictions

The New Orleans Saints (1-1) and the Carolina Panthers (0-2) meet in a Week 3 matchup Sunday at Bank of America Stadium. Kickoff is scheduled 1 p.m. ET (FOX). Below, we analyze Tipico Sportsbook‘s lines around the Saints vs. Panthers odds, and make our expert NFL picks and predictions.

The Saints played a defensive battle in their home opener against the Tampa Bay Buccaneers, coming up short in Week 2 by a 20-10 score. New Orleans has failed to cover both games to start the year.

The Panthers are 0-2 SU/ATS, losing both games outright as a small-number favorite. Carolina has lost its 2 games by a combined 5 total points.

These NFC South teams split their meetings last season, with the home team winning and covering each meeting. The Under has cashed in 3 in a row in the series.

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Saints at Panthers odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:12 a.m. ET.

  • Money line (ML): Saints -135 (bet $135 to win $100) | Panthers +115 (bet $100 to win $115)
  • Against the spread (ATS): Saints -2.5 (-117) | Panthers +2.5 (-103)
  • Over/Under (O/U): 41.5 (O: -108 | U: -112)

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Saints at Panthers key injuries

Saints

  • CB Paulson Adebo (ankle) questionable
  • TE Taysom Hill (rib) questionable
  • RB Alvin Kamara (rib) questionable
  • S Marcus Maye (rib) questionable
  • OT Ryan Ramczyk (elbow) questionable)
  • QB Jameis Winston (back, ankle) questionable

Panthers

  • CB Donte Jackson (hamstring) questionable

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Saints at Panthers picks and predictions

Prediction

Saints 21, Panthers 18

Money line

The SAINTS (-135) are worth a play but circle back around Sunday before finalizing your wager. With Winston on the injury report, and a 50-50 proposition to play, this could turn into a huge risk in a hurry if he is inactive.

Winston has 4 of his 33 vertebrae fractured, and now he is dealing with an ankle injury, too. If Winston is sidelined, veteran QB Andy Dalton would get the starting nod, so New Orleans would still be in decent hands.

Against the spread

The Saints -2.5 (-117) aren’t terribly overpriced, but there is just so much risk based on the QB situation. In addition, Kamara is also on the injury report and a 50-50 proposition. The Saints could go from Winston and Kamara playing, to Dalton and RB Mark Ingram II.

PASS, just play the money line instead.

Over/Under

UNDER 41.5 (-112) is worth playing lightly, regardless of the healthy of Winston and Kamara. Even if they play, the Under has hit in each of the past 3 meetings in this series.

The Under is 9-4 in the past 13 games inside the NFC South for New Orleans and is 7-2 in its last 9 games overall. The Under is 5-2 in the past 7 games for the Panthers inside the division, too.

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