Brian Fluharty-USA TODAY Sports

Before opening a three-game series against the Blue Jays in Toronto on Monday, the Red Sox placed closer Tanner Houck and outfielder Jarren Duran on the restricted list.

To take their place on the major-league roster, right-hander Connor Seabold and infielder Yolmer Sanchez were called up from Triple-A Worcester, the team announced.

Neither Houck or Duran are vaccinated against COVID-19 and therefore cannot travel to Canada. They will not receive pay or service time for the next three days and will instead work out at Fenway Park before rejoining the Red Sox in Chicago later this week.

Seabold, meanwhile, will make the second start of his big-league career at Rogers Centre on Monday night while filling in for the injured Garrett Whitlock. The 26-year-old made his major-league debut in a spot start against the White Sox last September and allowed two runs in three innings at Guaranteed Rate Field.

In 11 starts for the WooSox this season, Seabold has posted a 2.09 ERA and 2.99 FIP with 51 strikeouts to 14 walks over 51 2/3 innings of work. The 6-foot-3, 200-pound hurler works with a fastball, slider, changeup, and curveball and is currently regarded by Baseball America as the No. 10 pitching prospect in Boston’s farm system.

Unlike Seabold, Sanchez is not on Boston’s 40-man roster. That said, the Red Sox will be able to return the 29-year-old to Worcester without having to expose him to waivers following the conclusion of their series in Toronto.

Sanchez, who actually turns 30 on Wednesday, originally signed a minor-league deal with Boston back in February. The Venezuela native spent the first seven years of his major-league career with the White Sox and won the American League Gold Glove Award for second baseman in 2019.

In 68 games (265 plate appearances) with the WooSox this season, the switch-hitting Sanchez has batted .253/.381/.424 (120 wRC+) with 11 doubles, one triple, eight home runs, 29 RBIs, 32 runs scored, four stolen bases, 44 walks, and 60 strikeouts while seeing playing time at every infield position besides first base.

On Sunday, manager Alex Cora said that Sanchez will likely make his first start for the Red Sox at second base on Wednesday so that Trevor Story can get off his feet for two days as Boston is off on Thursday.

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