Update: Three people were killed in a crash on Interstate 81 in Washington County, Virginia, Tuesday, according to Virginia State Police.

Police said a 2011 Jeep Grand Cherokee was going south on Interstate 81 when it ran off the left side of the interstate into the median. The vehicle then crossed through the median, struck the guardrail, flipped onto its side and came to rest in a northbound lane of I-81, according to police.

A northbound 2020 Jeep Cherokee was unable to avoid striking the overturned vehicle in its lane, police said. The impact caused both vehicles to catch fire, police added.

A man and woman were killed in the Jeep Grand Cherokee, according to police. The man driving the Cherokee also died at the scene, police said.

Their remains have been sent to Roanoke for autopsy and positive identification.

The crash was near mile marker 24.

The crash remains under investigation.

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Emergency crews are at the scene of a vehicle crash along I-81 in the Meadowview, Virginia area.

Traffic is backed up in the northbound lanes of the interstate near mile marker 24.

Drivers are asked to avoid the area.