“Ghostbusters: Afterlife” actor Celeste O’Connor has been cast in “Madame Web,” an upcoming installment in Sony’s Universe of Marvel Characters.

O’Connor’s role has not been announced. They will appear in the comic-book adventure alongside Dakota Johnson, who is playing the title character, as well as Sydney Sweeney of “Euphoria” fame.

The movie will serve as an origin story for Madame Web, a clairvoyant whose psychic abilities allow her to see within the spider world itself. In the Marvel comics, Madame Web is a paralyzed, elderly woman with myasthenia gravis, a chronic autoimmune disorder requiring her to connect to a life support system resembling a spider web. Her supernatural abilities prove to be greatly beneficial to Spider-Man and his fellow arachnid allies, like Spider-Woman. Given her condition, though, she’s never battled villains herself.

S.J. Clarkson, a Marvel alum through “Jessica Jones” and “The Defenders,” is directing “Madame Web.” Matt Sazama and Burk Sharpless, the duo behind Jared Leto’s vampire antihero “Morbius,” are writing the screenplay.

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“Madame Web” is Sony’s first modern comic book adaptation to feature a woman in the headlining role. It is one of several Spider-Man related spinoffs in Sony’s pipeline, including “Kraven the Hunter,” featuring Aaron Taylor-Johnson and Ariana DeBose.

O’Connor will next be seen in writer-director Zach Braff’s feel-good drama “A Good Person,” which also stars Morgan Freeman and Florence Pugh. Most recently, O’Connor was seen in “Ghostbusters: Afterlife” and the Joey King-led science-fiction romantic drama “The In Between.” Their other credits include Blumhouse’s slasher movie “Freaky” and Netflix’s “Irreplaceable You.”

O’Connor is represented by Paradigm, Authentic Talent & Literary Management and Granderson Des Rochers.