Jimmy Kimmel tests positive for COVID-19 again, John Mulaney, Andy Samberg to fill in on 'Live'

Jimmy Kimmel (L), and his wife, Molly McNearney, arrive for The Kennedy Center's presentation of the annual Mark Twain Prize for American Humor on April 24. Kimmel has tested positive for COVID-19 once again. File Photo by Mike Theiler/UPI John Mulaney appears backstage during the 70th annual Primetime Emmy Awards in September 2018. File Photo by Christine Chew/UPI Andy Samberg (R) and his wife, Joanna Newsom, arrive for the Vanity Fair Oscar party in February 2020. File Photo by Chris Chew/UPI Jimmy Kimmel (L) and his wife, Molly McNearney, arrive at the John F. Kennedy Center for the Performing Arts in October 2017. File Photo by Mike Theiler/UPI Jimmy Kimmel (L) and his wife, Molly McNearney, attend the Vanity Fair Oscar Party in February 2017. File Photo by Christine Chew/UPI

May 18 (UPI) -- Jimmy Kimmel has announced on Twitter that he has once again tested positive for COVID-19 for the second time in May.

Kimmel also stated that John Mulaney and Andy Samberg will step in as guest hosts for his late night talk show Jimmy Kimmel Live on Wednesday.

Advertising

"I'm such a positive person, I tested positive AGAIN. I am feeling fine - the great John @Mulaney & Andy Samberg @TheLonelyIsland have graciously agreed to host @JimmyKimmelLive for me tomorrow," the comedian tweeted.

Kimmel only recently returned to hosting his late night talk show after testing positive earlier in May. Comedian Mike Birbiglia stepped in as guest host at the time.

Jimmy Kimmel Live is set to feature Cheryl Hines, Milo Ventimiglia, Jessie Buckley, Ryan Seacrest and Joe Keery this week. Gang of Youths, Franz Ferdinand and Train are set as the musical guests.

Stephen Colbert of The Late Show had also tested positive for COVID-19 in April, but has recently returned to resume his hosting duties.