Cronenworth (groin) is starting at second base and batting cleanup in Wednesday's game against the Angels.
The 28-year-old had been dealing with a groin injury this spring, but he'll make his debut Wednesday. Cronenworth had a strong season in 2021, hitting 21 home runs and driving in 71 runs while slashing .266/.340./.460. He will look to build on his All-Star campaign in 2022 on a Padres team that's set to contend for a pennant in the National League.