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  • RESEARCH HIGHLIGHT

Synthetic viral lookalikes sneak gene-editing tools into cells

Specially engineered particles allow researchers to fix blindness-causing genes in mice.
Artwork of an adenine base editor bound to a DNA strand

A type of genome-editing tool called a base editor (bound to DNA; artist’s illustration) can be smuggled into an animal’s cells by a virus-like particle. Credit: Ramon Andrade 3DCIENCIA/Science Photo Library

Researchers have engineered virus-like particles that efficiently deliver gene-editing proteins to specific organs in living animals1.

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Nature 601, 300 (2022)

doi: https://doi.org/10.1038/d41586-022-00068-9

References

  1. Banskota, S. et al. Cell https://doi.org/10.1016/j.cell.2021.12.021 (2022).

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