New graft strategy may improve outcomes for blood stem cell recipients

A special type of MRI found lung abnormalities in patients who had previously had COVID-19, even those who had not been hospitalized with the illness, according to a new study published in the journal Radiology. "In a collaboration between the University of Oxford and the University of Sheffield, we have...

A team of researchers led by NTU scientists have discovered why patients with non-alcoholic fatty liver disease (NAFLD) are at higher risk of cardiovascular disease, thus shedding light on why the leading cause of mortality in NAFLD patients is cardiovascular complications instead of liver damage. The researchers found that NAFLD...

An FDA-approved drug to lower blood sugar in adults with type 2 diabetes also may decrease blood vessel dysfunction associated with aging, according to a new study from the University of Missouri School of Medicine. Researchers initially examined the role aging plays in human blood vessel function and stiffness. Then...

For more than 20 years, scientists have known that people with hypertension, diabetes, high cholesterol, or obesity have a higher likelihood of developing Alzheimer's disease. The conditions can all affect the brain, damaging blood vessels and leading to strokes. But the connection between vascular disease in the brain and Alzheimer's has remained unexplained despite the intense efforts of researchers.

A recent study jointly conducted by the LKS Faculty of Medicine, The University of Hong Kong (HKUMed) and the Faculty of Medicine, The Chinese University of Hong Kong (CU Medicine) shows that vaccinated individuals can develop more robust and broadly reactive antibody responses against SARS-CoV-2 variants than unvaccinated individuals after an omicron infection. This highlights the need for COVID-19 vaccination for unvaccinated people even after an SARS-CoV-2 infection. The findings are now published in Eurosurveillance.

Prone positioning does not significantly reduce the risk of intubation in hospitalized patients experiencing acute hypoxemic respiratory failure from COVID-19, according to the COVI-PRONE trial. However, patients receiving high-flow oxygen may benefit from awake prone positioning. This international, multi-center randomized clinical trial also found that prone positioning had no significant effect on death and the length of stay in the intensive care unit or hospital.

Atherosclerosis, a buildup of plaque, can lead to heart disease, artery disease, and chronic kidney disease and is traditionally treated by inserting and inflating a balloon to expand the artery. Other treatments based on lasers can remove blockages rather than simply compressing them but are used infrequently, because they have a high risk of complication and low efficacy.

The risk of having a future stroke caused by a severe blockage in an artery in the neck that is not currently causing any symptoms is so low that most patients with this condition—asymptomatic carotid stenosis—could potentially be treated with the newest medications and may not require surgery, new Kaiser Permanente research suggests.

We've all become familiar with virus mutations over the course of the pandemic, and can all probably list off the COVID variants including alpha, delta and omicron. But now we're hearing more and more about subvariants, as omicron mutates into omicron BA.2, omicron BA.4, omicron XE, and more. We know...

In Northwest Ethiopia, 35 percent of patients with dyspepsia have peptic ulcer disease, with risk factors including Helicobacter pylori (H. pylori) infection and nonsteroidal anti-inflammatory drug (NSAID)/acetylsalicylic acid (ASA) use, according to a study published online April 5 in BMC Gastroenterology. Belete Assefa, from the University of Gondar in Ethiopia,...

Scientists have demonstrated that normal brain aging is accelerated by approximately 26% in people with progressive type 2 diabetes compared to individuals without the disease, reports a study published today in eLife. The authors evaluated the relationship between typical brain aging and that seen in type 2 diabetes, and observed...

A study led by experts from NHS Golden Jubilee and the University of Glasgow into the effects of COVID-19 on Scottish patients in Intensive Care Units (ICUs) has confirmed evidence that the virus is associated with impaired function of the right side of the heart. Specialists at NHS Golden Jubilee's...

Colonoscopies performed with computer-aided detection, or artificial intelligence, (AI) saw an increase in the overall rate of detection of adenoma, or cancerous and precancerous polyps, by 27% in average-risk patients, according to new data presented today at the Digestive Disease Week Annual Meeting. The results of the prospective, randomized, multicenter...

A new study from The University of Toledo College of Medicine and Life Sciences has shown gut bacteria can reduce the effectiveness of certain blood pressure drugs. The research, published this month in the journal Hypertension, offers the first clues to what has been an elusive mystery—why do some people not respond well to medication?

Higher red cell distribution width (RDW) is associated with increased rates of in-hospital mortality and hospital re-admission among older (>60) patients, new research led by investigators at Sutter Health's San Francisco Coordinating Center (SFCC) in San Francisco, CA has shown. Results of a retrospective analysis were published this month in...

Even vaccinated people with mild breakthrough COVID-19 infections can experience debilitating, lingering symptoms that affect the heart, brain, lungs and other parts of the body, according to new research from Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care System. The study of...

While most commonly known as "the powerhouses of the cell" because of their energy producing capabilities, mitochondria also play important roles in regulating the health of cells. These important structures can be damaged by alcohol consumption, which can cause them to rupture and release their DNA, proteins and lipids, collectively known as "damage associated molecular patterns (DAMPs)."

A research team led by Professor Kelvin Yeung Wai-kwok and Dr. Jasper Chan Fuk-woo from the LKS Faculty of Medicine, The University of Hong Kong (HKUMed) discovered that SARS-CoV-2 infection can cause inflammatory activation of bone resorption cells, leading to severe bone loss during the acute and post-recovery phases of COVID-19. The findings of this study provide insights into the possible long-term complications of COVID-19 and have been published in the international peer-reviewed journal Nature Communications.

A breast cancer patient's perspective on their physical well-being can provide a better indication of their response to cancer treatment than clinician-based tools, a new study has found, highlighting the importance of shared decision-making in the treatment process. The research also identified differences between clinician-based data and the patient-reported data,...

Huntsman Cancer Institute researchers discovered people with a certain polyp syndrome and their first-degree relatives are at increased risk for colorectal cancer. In addition, people with certain colon lesions are also at an at increased risk. Lead authors Karen Curtin, Ph.D., epidemiologist at Huntsman Cancer Institute and associate professor of internal medicine at the University of Utah (U of U), and Priyanka Kanth, MD, associate professor of internal medicine at MedStar Georgetown University Hospital and adjunct associate professor of internal medicine at the University of Utah, answer questions about the study published in The American Journal of Gastroenterology.