Five years of high-dose vitamin D did not affect incidence of cardiovascular disease or cancer

MILLIONS of Brits have been urged to take up a rapid test to see if they have bowel cancer. The Health Secretary has called on men over 60 to make sure they have the life-saving checkups. It couldn't be easier - with a home testing kit on offer, or use...

Unmarried heart failure patients appear less confident in managing their condition and more socially limited compared to their married counterparts, according to research presented May 21 at Heart Failure 2022, a scientific congress of the European Society of Cardiology (ESC). These differences may have contributed to the worse long-term survival observed in unmarried patients.

Primary immunodeficiency disorders (PID) can result in chronic and sometimes life-threatening infections. More than 450 PIDs have been described, but timely and accurate diagnoses remain a challenge. In a new study in The Journal of Molecular Diagnostics, investigators used next-generation sequencing technology to test a DNA panel of 130 different immune system genes from 22 study participants. They found that many patients had inherited a genetic defect that caused a disorder in their immune system. These findings will facilitate better treatment options and earlier diagnosis in family members who may have inherited the same genetic abnormality.

A voice analysis app used by heart failure patients at home recognizes fluid in the lungs three weeks before an unplanned hospitalization or escalation in outpatient drug treatment. The late breaking research was presented on May 21 at Heart Failure 2022, a scientific congress of the European Society of Cardiology (ESC).

A new study has found that a simple, one-off treatment was able to prevent long term side effects of cancer radiotherapies. There are about 2 million cancer survivors in the UK, and many of them face premature memory loss and faster occurrence of various diseases resembling premature aging, to which sadly, there is no cure. This is thought to be caused by side effects of toxic cancer chemotherapies and radiotherapies, which aim to treat cancer cells but can also damage normal cells.

The pharmaceutical company Pfizer has voluntary recalled a blood pressure medication for the second time in a month. Pfizer is recalling five lots of blood pressure medicine Accupril because of elevated levels of a nitrosamine, Nnitroso-quinapril, the company said in a news release posted Friday on the FDA website. Nitrosamines...

Walking at a brisk pace for just 75 minutes every week could cut your risk of depression, a new study finds. The World Health Organization recommends everyone should exercise for at least two-and-a-half hours every seven days. But researchers at Cambridge University, England, found adults who got half as much...

Though helpful for cleaning and disinfecting, Lysol contains a number of harmful chemicals that can irritate your eyes, skin, and respiratory system.

An otherwise healthy 30-year-old man had a hoarse voice and back pain that wouldn't go away. Doctors found a 4-inch tumor that spread quickly.

Christine Bronstein took at home colon cancer test after seeing blood in her stool. It was positive, but her doctor texted: "You don't have cancer :)"

In a follow-up on the 14th Ebola Virus Disease (EVD) outbreak in the Democratic Republic of the Congo (DRC) (HERE and HERE), the World Health Organization (WHO) tweeted today:. Health authorities in #DRC confirmed a 2nd case of #Ebola in Mbandaka on 25 April. The 25-year old woman, now deceased, began experiencing symptoms 12 days earlier. Investigations indicate that as the 1st case patient’s sister-in-law, she was a high-risk contact.

Tragic events like wars, famines, earthquakes, and accidents create fearful memories in our brain. These memories continue to haunt us even after the actual event has passed. Luckily, researchers from Tokyo University of Science (TUS) have recently been able to understand the hidden biochemical mechanisms involved in the selective suppression of fearful memories, which is called fear extinction. The researchers, who had previously demonstrated fear extinction in mice using the chemically synthesized compound "KNT-127," have now identified the underlying mechanism of this compound's action. Their findings have been published recently in Frontiers in Behavioral Neuroscience.

Shielding those vulnerable to COVID-19, while allowing the virus to spread, largely unmitigated, through the rest of the population, would have failed according to a new modeling paper published today in PLOS Global Public Health by University of Bath scientists. Shielding strategies or "focused protection", as advocated for in the...

Breakthrough COVID-19 cases resulting in infections, hospitalizations and deaths are significantly more likely in cancer and Alzheimer's patients, according to two new studies from researchers at the Case Western Reserve University School of Medicine. People within these diseases are often more susceptible to infection in general, the researchers explained, and...

One in eight people who were hospitalized with COVID-19 between May 2020 and March 2021 were later diagnosed with myocarditis, or heart inflammation, according to major new research into the clinical long-term effects of COVID-19. The largest study of its kind to date was led by the University of Glasgow...

A lifestyle intervention program of increased physical activity, healthy eating and aiming for weight loss of 7% or more, or taking the medication metformin were effective long-term to delay or prevent Type 2 diabetes in adults with prediabetes. Neither approach, however, reduced the risk of cardiovascular disease for study participants over 21 years of the study, according to the findings of the multicenter Diabetes Prevention Program Outcomes Study (DPPOS), published today in the American Heart Association's flagship, peer-reviewed journal Circulation.

New analysis finds more than half of U.S. adolescents and young adults with sarcoma, a type of cancer in the bones or soft tissues, are often prescribed opioids to treat their pain. Nearly one-quarter of these patients continue to use opioids after treatment is completed according to findings published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society.

The drug gabapentin, currently prescribed to control seizures and reduce nerve pain, may enhance recovery of movement after a stroke by helping neurons on the undamaged side of the brain take up the signaling work of lost cells, new research in mice suggests. The experiments mimicked ischemic stroke in humans,...

DEAR MAYO CLINIC: I was recently diagnosed with osteoporosis and my health care team suggested that I eat a bone-healthy diet to prevent more issues and maintain strong bones as I age. What is osteoporosis, and how can I maintain a bone-healthy diet?. ANSWER: Osteoporosis is a condition that causes...

Getting the COVID-19 vaccination strengthened one type of immune response to the SARS-CoV-2 virus in inflammatory bowel disease (IBD) patients even though they were taking immunosuppressant medication, according to investigators at Cedars-Sinai. The findings of two studies focused on this topic have been published in the journals IBD, of the...