This is an exciting moment for us to announce the winners of the 2020 Sanofi-Cell Research Outstanding Review Article Award: Dr Eran Elinav,1 for his review paper entitled “Interaction between microbiota and immunity in health and disease”; and the Sanofi-Cell Research Outstanding Research Article Award: Drs Lu Lu, Shibo Jiang, Yun Zhu,2 for their research paper entitled “Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion”; Drs Hongkui Deng and Tuoping Luo,3 for their research paper entitled “Elimination of senescent cells by β-galactosidase-targeted prodrug attenuates inflammation and restores physical function in aged mice”. The award consists of a prize of ¥25,000 for the Outstanding Review Article Award and ¥40,000 for the Outstanding Research Article Award sponsored by Sanofi.
Let us take a brief look at these three excellent works. In the award-winning review article from Dr Elinav and colleagues,1 published in the June 2020 issue, the authors systematically discussed host immune-microbiome interactions and their potential effects on human health and disease risk, providing a comprehensive picture of the microtiota-immunity realm. In the first award-winning research article, published in the April 2020 issue, Drs Lu Lu, Shibo Jiang, Yun Zhu and colleagues,2 reported a pan-coronavirus fusion inhibitor that showed potent inhibition of infection of several human coronaviruses, and exhibited both prophylactic and therapeutic efficacy in mouse model. This is a timely finding on the potential treatments against SARS-CoV-2 infection in the very early phase of COVID-19 outbreak. In the second award-winning research article, published in the July 2020 issue, Drs Deng, Luo and colleagues3 designed and developed a novel compound based on the increased activity of lysosomal β-galactosidase, which could eliminate mouse and human senescent cells, and restore physical function in aged mice. Clearing senescent cells is a promising approach to treat age-related diseases and improve physical function. This work opens a new avenue for treating aging-associated diseases.
Please join us to congratulate Dr Elinav, Drs Deng and Luo, Drs Lu, Jiang and Zhu on their winning of the 2020 Sanofi-Cell Research Outstanding Paper Award.
References
Zheng, D. et al. Cell Res. 30, 492–506 (2020).
Xia, S. et al. Cell Res. 30, 343–355 (2020).
Cai, Y. et al. Cell Res. 30, 574–589 (2020).
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Cell Research Editorial Team. Sanofi-Cell Research outstanding paper award of 2020. Cell Res 31, 1225 (2021). https://doi.org/10.1038/s41422-021-00593-8
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DOI: https://doi.org/10.1038/s41422-021-00593-8