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First look: Tampa Bay Buccaneers at Indianapolis Colts odds and lines

The Indianapolis Colts (6-5) host the Tampa Bay Buccaneers (7-3) Sunday for their Week 12 meeting at Lucas Oil Stadium. Below, we look at the Buccaneers vs. Colts odds and lines; check back for our NFL picks and predictions.

Tampa Bay boat raced the New York Giants 30-10 easily covering as 11-point favorites on Monday Night Football in Week 11. The Bucs outgained the Giants 402-215 in total yardage, possessed the ball for additional 11 minutes and converted 13 more first downs.

The Bucs have a two-game lead over the New Orleans Saints in the NFC South.

Also see: All Week 12 odds and lines

Indianapolis put a 41-15 whooping on the Buffalo Bills as 7-point road underdogs this past weekend. It was an all-time game for Colts RB Jonathan Taylor, who scored five TDs from scrimmage (four rushing TDs and one receiving) and 204 all-purpose yards.

The Colts sit two games behind the Tennessee Titans for first in the AFC South, but Tennessee owns the tiebreaker after winning both regular-season meetings vs. Indianapolis.

Buccaneers at Colts odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Tuesday at 7:55 a.m. ET.

  • Money line: Buccaneers -140 (bet $140 to win $100) | Colts +115 (bet $100 to win $115)
  • Against the spread (ATS): Buccaneers -2.5, -120 (bet $120 to win $100) | Colts +2.5, +100 (bet $100 to win $100)
  • Over/Under (O/U): 51.5, O: -103 (bet $103 to win $100) | U: -117 (bet $117 to win $100)

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2021 betting stats:

  • ML: Buccaneers 7-3 | Colts 6-5
  • ATS: Buccaneers 4-6 | Colts 7-4
  • O/U: Buccaneers 5-5 | Colts 7-4

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Buccaneers at Colts head-to-head

This last time these teams met (Dec. 2019) QB Jacoby Brissett was under center for the Colts, and the Bucs had QB Jameis Winston as their playcaller – so those results don’t apply to this game.

Tampa Bay is 4-9 ATS as a road favorite since the beginning of last season. Also, including Week 11, the Bucs have played in three Monday Night Football games since the start of 2020. Tampa Bay is 0-2 overall and ATS in its first two games following Monday Night Football in the Brady era.

Indianapolis is 3-3 ATS at home this year but 5-2 ATS as an underdog with a plus-7.1 spread differential.

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