The Premier League champions will be looking to get back to winning ways in Europe after suffering a 2-0 defeat against PSG in September.
Despite sealing an emphatic 6-3 victory over RB Leipzig on matchday one, City remain third in the group as a result of their loss in Paris, where Idrissa Gueye and Lionel Messi sealed a smash-and-grab win for the Parisiens.
Here are the confirmed lineups from Tuesday's clash at the Jan Breydel Stadium-
Club Brugge: Mignolet; Mata, Hendry, Sobol; Sowah, Vanaken, Balanta, Rits, Nsoki; Lang, De Ketelaere
Substitutes: Lammens, Maouassa, Ricca, Vormer, Izquierdo, van der Brempt, Dost, Mechele, Mbamba-Muanda
Manchester City: Ederson; Walker, Dias, Laporte, Cancelo; Rodri, Bernardo, De Bruyne; Mahrez, Foden, Grealish
Substitutes: Steffen, Carson, Ake, Zinchenko, Fernandinho, Gundogan, Palmer, Jesus, Sterling
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