The Academy graduate was named in the squad for the first time this season, after missing the start of the campaign while recovering from shoulder surgery.
Marcus entered the action as a second-half substitute and quickly scored his first goal of 2021/22, latching onto a pass from Victor Lindelof to calmly finish past Kasper Schmeichel.
Rashford’s goal made it 2-2 at the King Power Stadium, but unfortunately the game slipped away from United and the Reds suffered a 4-2 loss in the Premier League.
Taking to Twitter following the final whistle, Rashford admitted he was pleased to return but ultimately frustrated by a difficult defeat in the Midlands.