The Denver Broncos have opened as 3.5-point betting favorites over the Las Vegas Raiders in Week 6 of the 2021 NFL season, according to Tipico Sportsbook. The AFC West showdown will be played at Empower Field at Mile High in Denver.

The over/under for total points scored between the two teams has been set at 44.5.

Last week, the Broncos were considered 1.5-point underdogs against the Pittsburgh Steelers and they lost 27-19. The Raiders were considered 5.5-point favorites against the Chicago Bears last week and lost 20-9.

Combined, Denver and Las Vegas scored 28 points in Week 5. They allowed 47 combined points.

Both teams started the year 3-0 before losing consecutive games. The Broncos are 3-2 against the spread this season this while the Raiders are 2-3.

Las Vegas leads the all-time series against Denver 67-54-2, including four wins in their last five meetings with the Broncos. The last time these two teams played in Denver, the Raiders won 32-31 last season.