First look: Tampa Bay Buccaneers at Philadelphia Eagles odds and lines

USA Today Sportsbookwire

The Tampa Bay Buccaneers (4-1) head to the "City of Brotherly Love" for a Thursday Night Football Week 6 showdown with the Philadelphia Eagles (2-3) at Lincoln Financial Field. Kickoff is scheduled for 8:20 p.m. ET. Below, we look at the Buccaneers vs. Eagles odds and lines; check back for our NFL picks and predictions.

Tampa Bay beat the brakes off of the Miami Dolphins 45-17 as an 11-point road favorite in Week 5 and QB Tom Brady had his best game of the season in the process. Brady completed 30-of-41 passes for 411 yards with a 5 TD to 0 INT ratio and a 144.4 QB Rating.

Philadelphia rallied back from a 12-point deficit to upset the Carolina Panthers 21-18 as a 2.5-point road underdog. The Eagles defense shut down Carolina's aerial attack as it held QB Sam Darnold to just 177 passing yards, intercepting 3 of his passes and sacking Darnold three times.

Buccaneers at Eagles odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports' betting odds for a full list. Lines last updated Monday at 11:40 a.m. ET.

Money line: Buccaneers -320 (bet $320 to win $100) | Eagles +250 (bet $100 to win $250)
Against the spread (ATS): Buccaneers -6.5, -120 (bet $120 to win $100) | Eagles +6.5, +100 (bet $100 to win $100)
Over/Under (O/U): 51.5, O: -105 (bet $105 to win $100) | U: -115 (bet $115 to win $100)

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2021 betting stats:

ML : Buccaneers 4-1 | Eagles 2-3
ATS : Buccaneers 2-3 | Eagles 2-3
O/U : Buccaneers 4-1 | Eagles 2-3

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Buccaneers at Eagles head-to-head

There isn't a lot to glean from the previous Buccaneers-Eagles meetings as Tampa Bay last beat Philly 27-21 in Sept. 2018. The Bucs were led by QB Ryan Fitzpatrick and the Eagles had 2017 Super Bowl MVP QB Nick Foles under center.

The last time Brady faced the Eagles was as a member of the New England Patriots in 2019 where he and the Patriots won 17-10. Also, there was Super Bowl LII when Brady was outdueled by Foles despite passing for 505 yards with a 3:0 TD:INT ratio and a 115.4 QB Rating.

Since the start of the last season (the beginning of the Tompa Bay era), the Bucs are 4-6 ATS as a road favorite with a plus-4.3 spread differential. Philly is 0-2 ATS with a minus-4.0 spread differential at home this season in head coach Nick Sirianni's first year on the job.

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