World Cup qualifying in South America features one of the biggest rivalry games around as Argentina host Uruguay on Sunday night. The reigning Copa America champions are 5-4-0 and in second place in the table, sitting in a comfortable position, while Uruguay are 4-4-2 but have Colombia and Paraguay breathing down their necks with eight games to go.

Here's are storylines, how you can watch the match and more:

How to watch and odds

  • Date: Sunday, Oct. 10 | Time: 7:30 p.m. ET
  • Location: Estadio Monumental -- Buenos Aires, Argentina
  • TV and live stream: fuboTV (Try now)  
  • Odds: Argentina -167; Draw +240; Uruguay +550 (via Caesars Sportsbook) 

Storylines

Argentina: On a 23-match unbeaten streak, the Copa champs finally have a foundation for a promising future that includes young talent. There will be growing pains along the way, but this team has been really impressive under Lionel Scaloni in 2021. Expect them to control the ball against Uruguay and have the most chances, but it is going to be physical and like a chess match. If Lionel Messi and company can use quick touches to get into space in the attacking third, they should put themselves in a position to score multiple goals and take all three points.

Uruguay: When they play Bolivia, the attack is on fire with six goals in their last two games, but against everybody else, this team is struggling. Uruguay have scored two goals in their last four games when facing South American opponents not named Bolivia. In fact, against other South American opponents, they've failed to score multiple goals in their last 10, including the 1-0 loss to Argentina in the Copa America this summer. It hasn't been due to a lack of chances, rather a lack of sharpness. Can they get it going against an Argentina team that conceded once in its last four games and has not allowed multiple goals in its last 10?

Prediction

Luis Suarez scores for Uruguay, but a Lionel Messi free kick in the second half earns the draw. Pick: Argentina 1, Uruguay 1