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Week 5 staff predictions: Jacksonville Jaguars vs. Tennessee Titans

John Reid
Florida Times-Union
Jaguars linebacker Myles Jack responds after a tackle on Titans running back Derrick Henry in December 2020.

GENE FRENETTE

Jaguars 27, Titans 20

This is not a misprint. Even with DistractionGate, I haven't been able to shake the feeling after seeing the Titans' bizarre 27-24 overtime loss to the New York Jets that this is the week the Jaguars' misery ends. Derrick Henry has had one monster game each of the last three years against the Jaguars, but never early in the season. If Trevor Lawrence can stay turnover-free again, he gets his first NFL win against a mediocre Tennessee defense.

Season record: 3-1

JOHN REID

Titans 24, Jaguars 17

Coach Urban Meyer and the Jaguars need a win badly. But not this time, not against the projected favorite in the AFC South - Titans. The Titans are coming off a loss to the New York Jets and that probably didn't sit well with Yulee native Derrick Henry, who is going to break loose against the Jaguars.  

Season record: 3-1

JUSTON LEWIS

Jaguars 28, Titans 17

Derrick Henry will rush for more than 100 yards and score two touchdowns, but the Jaguars will win.  Trevor Lawrence will take care of the ball again this week and will score at least one rushing touchdown. I think the Jaguars put pressure on Ryan Tannehill and forces him into poor throws. 

Note: Juston Lewis is pinch-hitting this week for Garry Smits, who is on assignment. 

Season record: 3-1

MICHAEL DIROCCO, ESPN

Titans 21, Jaguars 17

The Jags will be able to pressure Ryan Tannehill and force a couple turnovers.  But Derrick Henry will be the difference.

Season record: 3-1