NLDS Game 1: Los Angeles Dodgers at San Francisco Giants odds, picks and prediction

The Los Angeles Dodgers and San Francisco Giants open their National League Division Series Friday at Oracle Park in a matchup of the majors' best two records. First pitch is scheduled for 9:37 p.m. ET (TBS). Let's analyze the lines around the Dodgers vs. Giantsodds with MLB picks and predictions.

The Giants won the NL West and the league's top seed behind an MLB-best 107-55 regular-season record. The Dodgers, who finished 1 game back at 106-56, beat the St. Louis Cardinals 3-1 on LF Chris Taylor's 2-run, 2-out, walk-off homer in Wednesday's NL Wild Card Game at Dodger Stadium.

Dodgers RHP Walker Buehler (16-4, 2.47 ERA) makes his 34th start. He has a 0.97 WHIP, 2.3 BB/9 and 9.2 K/9 through 207 2/3 IP.

• Last outing: Win, 5 IP, 1 ER, 3 H, 1 BB, 11 K in 10-3 home victory vs. Milwaukee Brewers Sunday
• Career vs. Giants: 7-1, 2.55 ERA, 1.12 WHIP in 11 starts and two relief appearances

Giants RHP Logan Webb (11-3, 3.03 ERA) makes his 27th start and 28th appearance. He has a 1.11 WHIP, 2.2 BB/9 and 9.6 K/9 through 148 1/3 IP.

• Last outing: Win, 7 IP, 4 ER, 6 H, 0 BB, 8 K in 11-4 home victory vs. San Diego Padres Sunday that clinched the NL West title
• Career vs. Dodgers: 1-2, 3.64 ERA, 1.05 WHIP in six starts

Dodgers at Giants odds, lines, picks and prediction

MLB odds provided by Tipico Sportsbook; access USA TODAY Sports for a full list. Odds last updated at 8:19 a.m. ET.

• Money line: Dodgers -120 (bet $100 to win $120) | Giants +100 (bet $1600to win $100)
• Against the spread/ATS: Dodgers -1.5 (+145) | Giants +1.5 (-180)
• Over/Under: 7.5 (O: +112 | U: -140)

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Prediction

Giants 3, Dodgers 2

Money line (ML)

SAN FRANCISCO (+ 100) is the STRONGEST PLAY - 1½ times your usual wager.

At +100, the value is with the Giants. They not only finished with MLB's best overall record, but they posted the second-best home record (54-27).

A Dodgers' disadvantage is they'll be without 1B Max Muncy, who dislocated his elbow on the final day of the regular season and wasn't able to play in the NL Wild Card win. Muncy led the team in homers (36) and RBIs (94), runs (95) and on-base percentage among qualified hitters (.368).

But this is an extremely close matchup.

San Francisco won the season series 10-9, which included a walk-off victory by each club. Plus, there were 6-one run games with each team winning three apiece.

In Los Angeles' last two series trips to Oracle Park, the Giants took two of three each time.

Run line/Against the spread (ATS)

PASS despite the Giants owning the best ATS mark in the majors.

ATS records:

• Regular season: Dodgers 82-80 | Giants 98-64
• Postseason: Dodgers 1-0 | Giants 0-0

The -180 price on San Francisco +1.5 is a bit expensive. Plus, we're already invested on the Giants' money line.

Over/Under (O/U)

BET UNDER 7.5 (- 140).

O/U records:

• Regular season: Dodgers 71-81-10 | Giants 74-83-5
• Postseason: Dodgers 0-1 | Giants 0-0

Both starting pitchers were exceptional in the season series this year.

Buehler went 3-1 with a 2.19 ERA (37 IP, 9 ER) and 0.97 WHIP in six starts vs. the Giants in 2021. Logan was 1-0 with a 2.25 ERA (16 IP, 4 ER) and 0.69 WHIP in three starts vs. the Dodgers.

Runs will be tough to come by.

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