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First look: New York Giants at Dallas Cowboys odds and lines

The New York Giants (1-3), fresh off their first win of the year, hit the road in Week 5 to face the NFC East-leading Dallas Cowboys (3-1). Kickoff from AT&T Stadium is set for 4:25 p.m. ET. Below, we look at the Giants vs. Cowboys odds and lines; check back for our NFL picks and predictions.

The Giants finally picked up a win with a 27-21 overtime victory over the New Orleans Saints in Week 4. They rallied from being down 21-10 in the fourth quarter to tie the game and RB Saquon Barkley ended it with a six-yard touchdown run in the extra frame. Barkley finished with 52 rushing yards and a touchdown to go with 74 receiving yards and a score on five catches, while QB Daniel Jones threw for 401 yards and 2 TD.

Also see: All Week 5 odds and lines

The Cowboys won 36-28 over the Carolina Panthers, marking their third consecutive victory and Carolina’s first loss. RB Ezekiel Elliott had 143 rushing yards and a touchdown on 20 carries, while QB Dak Prescott threw 4 touchdown passes without an interception. CB Trevon Diggs picked off Panthers QB Sam Darnold twice, giving him 5 interceptions in the first four games of the season.

Giants at Cowboys odds, spread and lines

Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated Monday at 3:15 a.m. ET.

  • Money line: Giants +230 (bet $100 to win $230) | Cowboys -300 (bet $300 to win $100)
  • Against the spread (ATS): Giants +6.5, +100 (bet $100 to win $100) | Cowboys -6.5, -120 (bet $120 to win $100)
  • Over/Under (O/U): 52.5, O: -112 (bet $112 to win $100) | U: -108 (bet $108 to win $100)

Also see: Betting 101

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2021 betting stats:

  • ML: Giants 1-3 | Cowboys 3-1
  • ATS: Giants 2-2 | Cowboys 4-0
  • O/U: Giants 2-2 | Cowboys 3-1

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Giants at Cowboys head-to-head

The Giants-Cowboys rivalry goes all the way back to 1960. They have faced each other 118 times with the Cowboys leading the all-time series 69-47-2.

The Giants won their last matchup 23-19 at home in Week 17 of the 2020 season. However. the Cowboys had won seven in a row over the Giants prior to that meeting.

Prescott is 7-2 in his career against the Giants; New York has not won in Dallas since 2016.

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