The Sportsbook Wire team is here to help you with your Week 3 NFL picks. Our writers offer up their selections on the money line, spread and Over/Under for every game on the Week 3 slate. Visit SportsbookWire.com for more NFL picks and predictions throughout the season.
Week 3 begins with just seven undefeated teams at 2-0. At the other end, six are winless at 0-2. Among the undefeated are the reigning Super Bowl champion Tampa Bay Buccaneers, who have taken over the top spot as the favorites to win Super Bowl LVI in Feb. 2022.
Check out our staff predictions before locking in your Week 3 NFL picks.
Also see: Week 3 odds and lines
NFL Week 3 staff picks
2021-22 season standings
Odds provided by Tipico Sportsbook.
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