The manager made three alterations to the XI on duty at Young Boys with Raphael Varane, Scott McTominay and Mason Greenwood replacing Victor Lindelof, Donny van de Beek and Jadon Sancho.
Scott's return is a welcome boost after he made a speedy recovery from a minor groin operation during the international break.
"Scott's always been a physical monster and specimen, he's fit," Ole told MUTV. "Of course, we want to get him going as quick as we can. He's missed a bit of football but the operation was needed and why not put him back in?"
In a separate interview with Sky Sports, he added: “Scott and Fred, of course, they’re back in, they’re a partnership that we see here, we want to have their energy here today.