Many Americans take immune-weakening drugs that may reduce COVID vaccine effects

Knowridge Science Report
Knowridge Science Report
Credit: CC0 Public Domain

In a recent study published in JAMA Network Open, researchers found that nearly 3% of insured U.S. adults under 65 take medications that weaken their immune systems.

The study is based on data from over 3 million patients with private insurance.

The research is from Michigan Medicine. One author is Beth Wallace, M.D., M.Sc.

In the study, the team focused on patients’ use of immunosuppressive drugs, including chemotherapy medications and steroids such as prednisone.

Their analysis reveals nearly 90,000 people met the study criteria for drug-induced immunosuppression that may elevate the risk for severe COVID-19 symptoms and hospitalization if they became infected.

Two-thirds of them took an oral steroid at least once, and more than 40% of patients took steroids for more than 30 days in a year.

When the team of researchers examined the data, a vaccine against COVID-19 was not yet available outside clinical trials.

The evidence is growing, however, that taking immunosuppressive drugs may reduce the efficacy of the shot.

The team mentions several strategies, including holding medications around the time of vaccination and giving an extra “booster” shot, that scientists are testing to look into this question.

They also express concern over how this group of immunosuppressed patients should proceed following the CDC’s relaxation of masking and distancing guidelines for vaccinated people.

Moving forward, researchers need prospectively look at vaccine response in this vulnerable population.

If you care about COVID-19, please read studies about common gut inflammation linked to COVID-19 and findings of these two drugs may help you recover from severe COVID-19.

For more information about COVID-19 and your health, please see recent studies about common painkillers can boost or suppress COVID-19 depending on timing and results showing big differences between mild vs. severe COVID-19 cases.

Copyright © 2021 Knowridge Science Report. All rights reserved.

Comments / 196

Name Not Needed

Not they are sure trying to blame everything and everyone other than admitting that their vaccination doesn’t work aren’t they?

Gilbert Guerrero

It’s been the constant mantra that the vaccine was essential for the immunocompromised.Again, I say, what in the world are we talking about

Daniel McCoy

"We became conditioned, after about May or so, to wear a mask, wait in isolation and be saved by the vaccine. And wait for the vaccine. And all we could hear about is the vaccine."Indiscriminate vaccination is driving mutations, as the virus is mutating wildly to evade the injections. Their effectiveness, too, is rapidly waning. A study published in medRxiv, using data from the Mayo Clinic Health System, revealed that during periods of Alpha and Delta variant prevalence, Moderna's injection was 76% effective while Pfizer's effectiveness was only 42%.16. But nothing about health preventive measures. Nothing about health treatment measures. They just skipped the biggest and most efficient steps in combating the Covid Virus. Why?


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