The UNLV Rebels will take on the Iowa State Cyclones on Saturday, September, 18 at 10:30 p.m. ET at Allegiant Stadium in Las Vegas. The Rebels (0-2) enter the game in danger of letting their season get away from them after falling to FCS opponent Eastern Washington in their season opener and getting blown out by No. 23 Arizona State 37-10 last week. Meanwhile No. 14 Iowa State (1-1) is coming off a gut-wrenching 27-17 loss to in-state rival Iowa in the annual battle for the Cy-Hawk Trophy, and will be looking to take out their frustrations on a lesser opponent in UNLV. 

Iowa State is favored by 30 points in the latest UNLV vs. Iowa State odds from Caesars Sportsbook, and the over-under for total points scored is set at 52. Before entering any Iowa State vs. UNLV picks, you'll want to see the college football predictions and analysis from the proven computer model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of over $3,500 for $100 players on its top-rated college football picks against the spread. It also enters Week 3 of the 2021 season on a 67-50 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on UNLV vs. Iowa State and just revealed its picks and predictions. You can head to SportsLine now to see the model's college football picks. Here are several college football odds for UNLV vs. Iowa State:

  • UNLV vs. Iowa State spread: UNLV +30
  • UNLV vs. Iowa State over-under: 52 points
  • UNLV vs. Iowa State Moneyline: UNLV +2000, Iowa State -10000

What you need to know about UNLV

The Rebels got off to a strong start last week against Arizona State Sun Devils, but ultimately couldn't capitalize and ended up losing 37-10. Their only offensive touchdown against ASU came on a rush from quarterback Doug Brumfield

Through two contests, UNLV is averaging just 247 yards of total offense per game (103.5 passing, 143.5 rushing). For the Rebels to have any chance at keeping this game close, they will have to play much better on the offensive side of the ball. Running back Charles Williams has had a highly productive college career, and the Rebels will be counting on him to play at a high level against ISU. 

What you need to know about Iowa State

Iowa State came up short against the Iowa Hawkeyes on Saturday, falling 27-17. No one had a standout game offensively for Iowa State, but they did get scores from running back Breece Hall and wide receiver Tarique Milton. Quarterback Brock Purdy was benched against Iowa after throwing three interceptions. His replacement, Hunter Dekkers, completed 11-of-16 passes for 114 yards and a touchdown. 

On Monday, Iowa State head coach Matt Campbell reaffirmed his belief that Purdy is the best option to lead the Cyclones offense going forward. Facing an inferior opponent such as UNLV may be just what the doctor ordered for Purdy as the senior quarterback looks to regain his confidence.

How to make Iowa State vs. UNLV picks

The model has simulated UNLV vs. Iowa State 10,000 times and the results are in. We can tell you that the model is leaning over on the point total, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You can only see the model's UNLV vs. Iowa State pick at SportsLine.

So who wins Iowa State vs. UNLV? And which side of the spread hits in well over 50 percent of simulations? Visit SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks, and find out.