First look: Denver Broncos at Jacksonville Jaguars odds and lines

Ken Pomponio

Sportsbook Wire

The Jacksonville Jaguars (0-1) open up their 2021 home slate Sunday, Sept. 19 by welcoming the Denver Broncos (1-0) to TIAA Bank Field for a 1 p.m. ET kickoff. Below, we look at the Broncos-Jaguars odds and lines; check back for our NFL picks and predictions.

The Broncos notched their first September win since 2018 by dominating the host New York Giants 27-13 Sunday. Teddy Bridgewater, Denver's 11th starting quarterback since Peyton Manning retired following the 2015 season, passed his debut test with flying colors completing 28-of-36 passes for 264 yards, two touchdowns, and most importantly, committing no turnovers.

Von Miller returned after missing the 2020 season due to injury and had a pair of sacks as the Denver defense held the Giants to 314 yards and 13 points. Six of those came on Daniel Jones' last-ditch scramble on the game's final play for a touchdown.

The Broncos did lose leading receiver Jerry Jeudy (six catches for 72 yards) to a high-ankle sprain in the third quarter.

Earlier Sunday in Houston, the favored Jaguars were overwhelmed by the Texans 37-21, spoiling the NFL debuts of QB Trevor Lawrence and head coach Urban Meyer. Lawrence completed 28-of-51 passes for 332 yards and three TDs but also tossed a trio of interceptions in suffering his first regular-season loss since becoming a starter in high school.

The Jags were hurt by 10 penalties for 82 yards and surrendered 449 yards defensively to new starting QB Tyrod Taylor and the Texans while failing to force a turnover.

Broncos at Jaguars odds, spread and line

Odds provided by Tipico Sportsbook; access USA TODAY Sports' betting odds for a full list. Lines last updated Monday at 1:30 p.m. ET.

Money line: Broncos -270 (bet $270 to win $100) | Jaguars +210 (bet $210 to win $100)
Against the spread (ATS): Broncos -5.5, -120 (bet $120 to win $100) | Jaguars +5.5, -105 (bet $105 to win $100)
Total (O/U): 45.5, Over -110 (bet $110 to win $100) | Under -110 (bet $110 to win $100)

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2021 betting stats:

ML : Broncos 1-0 | Jaguars 0-1
ATS : Broncos 1-0 | Jaguars 0-1
O/U : Broncos 0-1 | Jaguars 1-0

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Broncos vs. Jaguars head-to-head

Jacksonville leads the all-time series 7-6 (8-5 against the spread), including a 26-24 win as 2.5-point road underdogs in their most recent meeting in Week 4 of the 2019 season.

This will be the teams' first meeting in Jacksonville since the Broncos' 20-10 road triumph in Week 13 of the 2016 season. The Jags, though, won three of the previous four series meetings at home.

Also see:All Week 2 odds and lines

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