First look: Dallas Cowboys at Los Angeles Chargers odds and lines

Joe Williams
Sportsbook Wire

The Dallas Cowboys (0-1) and Los Angeles Chargers (1-0) meet Sunday in Week 2 at SoFi Stadium in Los Angeles. Kickoff is scheduled for 4:25 p.m. ET. Below, we look at the Cowboys vs. Chargers odds and lines; check back for our NFL picks and predictions.

The Cowboys came up short Thursday night at the defending champ Tampa Bay Buccaneers, losing a 31-29 thriller. Dallas was able to cover the spread as a 10-point underdog, while QB Dak Prescott threw for 403 yards and three touchdowns in his return.

The Chargers headed to the nation's capital and scratched out a 20-16 win against the Washington Football Team as the Under connected. L.A. was good for 424 total yards, including 334 yards through the air.

Cowboys at Chargers odds, spread and line

Odds provided by Tipico Sportsbook; access USA TODAY Sports' betting odds for a full list. Lines last updated Monday at 8:19 a.m. ET.

  • Money line: Cowboys +122 (bet $100 to win $122) | Chargers -150 (bet $150 to win $100)
  • Against the spread (ATS): Cowboys +2.5, +100 (bet $100 to win $100) | Chargers -2.5, -125 (bet $125 to win $100)
  • Total (O/U): 52.5, Over -110 (bet $110 to win $100) | Under -110 (bet $110 to win $100)

PLAY: Try our new, free daily Pick'em Challenge and win. Play now !

2021 betting stats:

  • ML : Cowboys 0-1 | Chargers 1-0
  • ATS : Cowboys 1-0 | Chargers 1-0
  • O/U : Cowboys 1-0 | Chargers 0-1

WIN YOUR FANTASY FOOTBALL LEAGUE!

For 25 years, TheHuddle.com has been helping fantasy players just like you win. This year, it's your turn! Custom player rankings, tools and more to give you the edge over your competition.

Use code SBW21 to take 20% OFF a new subscription. Join now!

Cowboys at Chargers head-to-head

The Chargers and Cowboys haven't met since a Thanksgiving game Nov. 23, 2017, at AT&T Stadium in Arlington, Texas. L.A won 28-6 as QB Philip Rivers was still under center for the Bolts.

The last time the Chargers hosted the Cowboys was back on Sept. 29, 2013, with L.A. winning 30-21 as Rivers outdueled QB Tony Romo. The Chargers have won three in a row in this series with the Cowboys last winning Sept. 11, 2005.

If you're looking for more sports betting picks and tips, access all of our content at SportsbookWire.com. Please gamble responsibly.

Follow Joe Williams on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Access more NFL coverage:

TheHuddle Fantasy Football | BearsWire | BengalsWire | BillsWire | BroncosWire | BrownsWire | BucsWire | CardsWire | ChargersWire | ChiefsWire | CowboysWire | DolphinsWire | EaglesWire | FalconsWire | GiantsWire | JaguarsWire | JetsWire | LionsWire | NinersWire | PackersWire | PanthersWire | PatriotsWire | RaidersWire | RamsWire | RavensWire | SaintsWire | SeahawksWire | SteelersWire | TexansWire | TitansWire | VikingsWire | WashingtonFootballWire | DraftWire | TouchdownWire | TheListWire

Gannett may earn revenue from audience referrals to betting services. Newsrooms are independent of this relationship and there is no influence on news coverage. This information is for entertainment purposes only. We make no representations or warranties as to the accuracy, completeness, or reliability of any content.