First look: Arizona Cardinals at Tennessee Titans odds and lines, Julio Jones debuts for Titans
The Arizona Cardinals open their season on the road against the Tennessee Titans Sunday. Kickoff will be at 1 p.m. ET at Nissan Stadium. Below, we look at the Cardinals vs. Titans odds and lines; check back for our NFL picks and predictions.
The Cardinals enter the third year of QB Kyler Murray‘s career and Kliff Kingsbury’s time as head coach. They finished 8-8 in 2020 and just missed the postseason, and Murray was named to the Pro Bowl for the first time.
They added DE J.J. Watt, WR A.J. Green and C Rodney Hudson this offseason in an attempt to get them in position to make a postseason run for the first time in Murray’s career.
The Titans made the postseason for the third time in four seasons, going 11-5 and winning the AFC South. They lost in the first round of the playoffs to the Baltimore Ravens. They added WR Julio Jones and OLB Bud Dupree this offseason.
Cardinals at Titans odds, spread and line
- Money line: Cardinals +125 (bet $100 to in $125) | Titans -155 (bet $155 to win $100)
- Against the spread (ATS): Cardinals +2.5, +105 (bet $100 to win $105) | Titans -2.5, -130 (bet $130 to win $100)
- Total (O/U): 52.5, Over -108 (bet $108 to win $100) | Under -112 (bet $112 to win $100)
2020 betting stats:
- ML: Cardinals 8-8 | Titans 11-5 (0-1 postseason)
- ATS: Cardinals 7-9 | Titans 7-9 (0-1)
- O/U: Cardinals 5-11 | Titans 12-3-1 (0-1)
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Cardinals at Titans head-to-head
The Cardinals lead the all-time series 7-4 and won the last two matchups in 2017 and 2013. The two teams only meet once every four years.
Both have productive quarterbacks. Murray had 37 combined passing and rushing touchdowns in 2020, while Titans QB Ryan Tannehill had 40 combined scores.
Titans RB Derrick Henry led the NFL with 378 rushing attempts, 2,027 rushing yards and 17 rushing touchdowns.
Cardinals WR DeAndre Hopkins had 115 receptions in 2020 for 1,407 yards and 6 touchdowns.
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