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#Relapse

MedicalXpress

Putting the brakes on heroin relapse

Neuroscientists from the Medical University of South Carolina (MUSC) report in Science Advances that star-shaped brain cells known as astrocytes can "turn off" neurons involved in relapse to heroin. Drug-related cues in the environment can intensify the drive to seek drugs, leading to relapse. In this article, a team led by Peter Kalivas, Ph.D., and Anna Kruyer, Ph.D., both of the Department of Neuroscience, examined how astrocytes interact with neurons and whether astrocytes play an important role in regulating the response to drug cues.
MENTAL HEALTH
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News-Medical.net

Star-shaped brain cells can "turn off" neurons involved in heroin relapse

Neuroscientists from the Medical University of South Carolina (MUSC) report in Science Advances that star-shaped brain cells known as astrocytes can "turn off" neurons involved in relapse to heroin. Drug-related cues in the environment can intensify the drive to seek drugs, leading to relapse. In this article, a team led by Peter Kalivas, Ph.D., and Anna Kruyer, Ph.D., both of the Department of Neuroscience, examined how astrocytes interact with neurons and whether astrocytes play an important role in regulating the response to drug cues.
HEALTH
Picture for Star-shaped brain cells can "turn off" neurons involved in heroin relapse
physiciansweekly.com

Pediatric Hodgkin Lymphoma with Early-Stage, Low-Risk: Targeted Radiotherapy

Early-stage pediatric classic Hodgkin lymphoma was treated with response-adapted involved-field radiotherapy (IFRT) instead of systemic treatment in the Children’s Oncology Group (COG) study AHOD0431. For a study, researchers sought to determine the effects of PET1 (positron emission tomography response after 1 cycle) on IFRT results and relapse patterns. After...
CANCER
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psychreg.org

Researchers Identifies Brain Cells That Can Put the Brakes on Heroin Relapse

Neuroscientists from the Medical University of South Carolina (MUSC) report in the journal Science Advances that star-shaped brain cells known as astrocytes can ‘turn off’ neurons involved in relapse to heroin. Drug-related cues in the environment can intensify the drive to seek drugs, leading to relapse. A team...
wdfxfox34.com

How to Make a Relapse Prevention Plan for Long-Term Recovery

Originally Posted On: https://havendetoxne.com/relapse-prevention-plan-for-long-term-recovery/. People can stay in recovery for longer at lower relapse rates if they have a relapse prevention plan. A relapse prevention plan is a strategy for identifying and reducing the risks associated with relapse. Through relapse prevention strategies, you can reduce the chance of slipping back into old patterns of substance use, but you might be especially at risk of a relapse event within the first year of established recovery. Learn how relapse is part of the recovery process, and see what you can do to make a relapse prevention plan for long-term recovery.
Reddit

I didn’t mean to relapse

Doctors put me back on 2 mg Xanax bars after a traumatic experience I’m thinking about just going to get my medical card instead I used to be a xan addict and they still don’t care Any advice ? submitted by /u/LongjumpingCarob3271 [link] [comments]
Nature.com

Trogocytosis-mediated tumor relapse after CAR-NK cell therapy prevented by inhibitory CARs

CAR-mediated trogocytosis contributes to dysfunction of natural killer (NK) cells by promoting fratricide and is an important mechanism of relapse after CAR-NK cell therapy. This problem can be overcome using a dual-CAR strategy that incorporates a dominant-negative signal to prevent NK cell fratricide and exhaustion, while sparing the CAR-activating signal against tumor targets.
HEALTH
ascopost.com

Outcomes After Nonresponse and Relapse in Children and Young Adults Receiving Tisagenlecleucel for B-Cell ALL

In a retrospective study reported in the Journal of Clinical Oncology, Schultz et al found poor survival among children and young adults with lack of response to tisagenlecleucel for B-cell acute lymphoblastic leukemia (ALL). Salvage therapy after relapse was capable of inducing responses, but relapse with loss/downregulation of CD19 expression was associated with poor prognosis.
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