Treatment Paradigm for R/R Multiple Myeloma Continues to Expand

During the NCCN 2021 Congress: Hematologic Malignancies Natalie S. Callander, MD, discusses treatment options in relapsed/refractory multiple myeloma. While initial disease control in multiple myeloma has improved, relapse is almost always inevitable. However, there are many treatment options available for this patient population, according to a presentation at the NCCN 2021 Virtual Congress: Hematologic Malignancies.
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Alpha Paradigm Partners LLC Acquires 3,148 Shares of Inovalon Holdings, Inc. (NASDAQ:INOV)

Alpha Paradigm Partners LLC increased its holdings in shares of Inovalon Holdings, Inc. (NASDAQ:INOV) by 742.5% during the second quarter, according to the company in its most recent disclosure with the Securities and Exchange Commission (SEC). The institutional investor owned 3,572 shares of the technology company’s stock after purchasing an additional 3,148 shares during the quarter. Alpha Paradigm Partners LLC’s holdings in Inovalon were worth $122,000 as of its most recent filing with the Securities and Exchange Commission (SEC).
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Supervision Exists Everywhere: A Data Efficient Contrastive Language-Image Pre-training Paradigm

Supervision Exists Everywhere: A Data Efficient Contrastive Language-Image Pre-training Paradigm. ** Our code, dataset and models will be relased soon**. Recently, large-scale Contrastive Language-Image Pre-training (CLIP) (Radfordet al., 2021) has attracted unprecedented attention for its impressive zero-shot recognition ability and excellent transferability to downstream tasks. However, CLIP is quite data-hungry and requires 400M image-text pairs for pre-training, thereby restricting its adoption. This work proposes a novel training paradigm, Data efficient CLIP (DeCLIP), to alleviate this limitation. We demonstrate that by carefully utilizing the widespread supervision among the image-text pairs, our DeCLIP can learn generic visual features more efficiently. Instead of using the single image-text contrastive supervision, we fully exploit data potential through the use of (1) self-supervision within each modality; (2) multi-view supervision across modalities; (3) nearest-neighbor supervision from other similar pairs. Benefiting from these intrinsic supervision, our DeCLIP-ResNet50 can achieve 60.4% zero-shot top1 accuracy on ImageNet, which is 0.8% above the CLIP-ResNet50 while using 7.1× fewer data. Our DeCLIP-ResNet50 outperforms its counterpart in 8 out of 11 visual datasets when transferred to downstream tasks. Moreover, Scaling up the model and computing also works well in our framework.
The Slidell Independent

Ten years of Paradigm Health System proving their model

SLIDELL – Is it possible that a small group of doctors can actually change the entire health system as we know it today?. According to Kevin Schneider and his physician partners at Paradigm Health System, the answer is a resounding “yes.”. Founded almost 10 years ago, the Slidell based company...

A young, all-women ensemble upends the percussion paradigm

Percussion ensembles tend to be a guy thing - you know, dudes pounding on stuff. But here's something different. (SOUNDBITE OF RECAP'S "FEAR / RELEASE") CHANG: This is the percussion quartet called Recap. No guys in this group. It's made up of four young women of color from Rahway, N.J. They've just released their debut album, and our reviewer, NPR's Tom Huizenga, has been listening.
No Treble

Paradigm Blue: The Optimist

Paradigm Blue has released Transit, a 14-track album of original music. The trio includes. on bass, vocals, and keyboards, Juan Mantilla on guitar, and Steve Laur on drums and percussion. The band shared the background:. “For the three of us, ‘Transit’ represented an opportunity to revisit the musical loves of...

Kirkland Leads as Francisco Partners Invests in Legal Tech

Kirkland & Ellis advised Francisco Partners on the private equity firm’s investment in Paradigm, a provider of practice management software and integrated payments to the legal industry. Kirkland also advised Alpine Investors, the private equity firm whose portfolio-company, software platform ASG, launched Paradigm in 2006. Kirkland also advised Paradigm, according...

A New Paradigm for Business

It is often said that the only constant in life is change. We certainly have had a massive dose of change over the last 18 months. Along with a contentious presidential election, throw in a global pandemic and you have the makings of a seismic shift in markets, consumers, and business in general.

MagicCube Announces $15 Million Investment Round Led by Mosaik Partners, Advancing the Software-Based Security Paradigm Shift - WSAZ-TV

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Changing the Paradigm: Stretching and Mobility in Cycling

By Pat Casey — How many of you reading this article have been told to “stretch more” or “add some yoga” into your routine? Mobility practice and maintenance of your body’s functional ranges of motion are often the first items to fall off on our training calendars. Most riders I work with at Peak State Fit acknowledge that they need to improve their movement quality, but they let their maintenance routine take a back seat in their busy lives. Many will mention that they stretch, but don’t have any rhyme or reason or process of how long per stretch or why they are stretching the muscles they do.