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#Pancreatic Cancer

Roanoke Daily Herald

Virginia Lynn ‘Jinny’ Walston Shearin

Virginia Lynn “Jinny” Walston Shearin died peacefully on Thursday, Sept. 16, 2021, after a brief bout with pancreatic cancer. She was born to John Irwin Walston and wife Virginia Pope Walston on June 5, 1940. She married Jesse Shearin on March 31, 1961. Jinny and Jesse were blessed with three...
SCOTLAND NECK, NC
Picture for Virginia Lynn ‘Jinny’ Walston Shearin
MedicalXpress

Link between inflammation and pancreatic cancer development uncovered

A new discovery from researchers at The University of Texas MD Anderson Cancer Center has clarified the long-established connection between inflammation and pancreatic cancer development. According to the study published today in Science, pancreatic cells display an adaptive response to repeated inflammatory episodes that initially protects against tissue damage but can promote tumor formation in the presence of mutant KRAS.
CANCER
Picture for Link between inflammation and pancreatic cancer development uncovered
TRENDING TOPICS
WNCT

Va. woman to host walk in ENC to raise awareness and funds for cancer research

AYDEN, N.C. (WNCT) — One woman is working to make sure communities across Eastern North Carolina are aware of the ways to help battle cancer. It’s not just any normal walk, it’s a way for communities to get together for a greater purpose. That’s what one Virginia woman, originally from Ayden, is saying after her family has had generations experiencing cancer that they are fighting to end.

Scientists confirm link between inflammation and pancreatic cancer

In a new study from the University of Texas, researchers clarified the long-established connection between inflammation and pancreatic cancer development. They found pancreatic cells display an adaptive response to repeated inflammatory episodes that initially protects against tissue damage but can promote tumor formation in the presence of mutant KRAS. The...
CANCER
Nature.com

Multimetric feature selection for analyzing multicategory outcomes of colorectal cancer: random forest and multinomial logistic regression models

Colorectal cancer (CRC) is one of the most common cancers worldwide, and a leading cause of cancer deaths. Better classifying multicategory outcomes of CRC with clinical and omic data may help adjust treatment regimens based on individual’s risk. Here, we selected the features that were useful for classifying four-category survival outcome of CRC using the clinical and transcriptomic data, or clinical, transcriptomic, microsatellite instability and selected oncogenic-driver data (all data) of TCGA. We also optimized multimetric feature selection to develop the best multinomial logistic regression (MLR) and random forest (RF) models that had the highest accuracy, precision, recall and F1 score, respectively. We identified 2073 differentially expressed genes of the TCGA RNASeq dataset. MLR overall outperformed RF in the multimetric feature selection. In both RF and MLR models, precision, recall and F1 score increased as the feature number increased and peaked at the feature number of 600–1000, while the models’ accuracy remained stable. The best model was the MLR one with 825 features based on sum of squared coefficients using all data, and attained the best accuracy of 0.855, F1 of 0.738 and precision of 0.832, which were higher than those using clinical and transcriptomic data. The top-ranked features in the MLR model of the best performance using clinical and transcriptomic data were different from those using all data. However, pathologic staging, HBS1L, TSPYL4, and TP53TG3B were the overlapping top-20 ranked features in the best models using clinical and transcriptomic, or all data. Thus, we developed a multimetric feature-selection based MLR model that outperformed RF models in classifying four-category outcome of CRC patients. Interestingly, adding microsatellite instability and oncogenic-driver data to clinical and transcriptomic data improved models’ performances. Precision and recall of tuned algorithms may change significantly as the feature number changes, but accuracy appears not sensitive to these changes.
CANCER
dallassun.com

Link between inflammation and pancreatic cancer development

Washington [US], September 18 (ANI): A new discovery from researchers at The University of Texas MD Anderson Cancer Center has clarified the long-established connection between inflammation and pancreatic cancer development. The findings of the study were published in the journal 'Science'. According to the study, pancreatic cells display an adaptive...
CANCER
thehealthcareblog.com

A Man With Sudden Onset of Gastroparesis

Leo Dufour is not a diabetic. He is in his mid 50s, a light smoker with hypertension and a known hiatal hernia. He has had occasional heartburn and has taken famotidine for a few years along with his blood pressure and cholesterol pills. Over the past few months, he started...
bizjournals

Bay Area biotechs soar on coattails of AstraZeneca cancer drug study

Shares of a Bay Area biotech company shot up more than 157% and another climbed to a lesser degree Friday after a Big Pharma company reported that a cancer drug with a shared target appeared effective in fighting tumors. Both Corvus Pharmaceuticals Inc. (Nasdaq: CRVS) of Burlingame and Arcus Biosciences...
MEDICAL & BIOTECH
Daily Reflector

Brewster probe looks at deaths, building safety at ECU

A team investigating cancer deaths of several ECU professors have provided federal authorities with more information about the building they worked in. ECU’s Environmental Health and Safety Facilities Services team last week provided information about the A-Wing of the Brewster Building to the CDC’ National Institute for Occupational Safety and Health. The institute sought the information during an Aug. 24 meeting with ECU official after concerns about the building were raised by faculty.
GREENVILLE, NC
gantnews.com

The Medical Minute: Real-time Tumor Tracking Improves Cancer Cure Rates

Image-guided radiation therapy has evolved to include the ability to track tumors in real time during treatment. It’s improving cure rates and limiting side effects for a growing number of cancer patients. Think of it like radio making way for television. For more than a century, radiation therapy has been...
CANCER
Rocky Mount Telegram

Virginia Lynn Walston Shearin

Virginia Lynn Walston Shearin (“Jinny”) died peacefully on Thursday, September 16, 2021 after a brief bout with pancreatic cancer. She was born to John Irwin Walston and wife Virginia Pope Walston on June 5, 1940. She married Jesse Shearin on March 31, 1961. Jinny and Jesse were blessed with 3 children: Jesse III, James, and William (“Will”); 9 grandchildren; and 1 one great-grandchild. Jinny and Jesse both grew up in Scotland Neck and returned home in 1982. It is the wish of the family that in lieu of flowers gifts be made directly to Scotland Neck Rising, P. O. Box 160, Scotland Neck, NC 27874 or online by visiting tmcfunding.com/search then type Jinny Shearin. Because the children and grandchildren live and work in various locations around the country, the family has chosen to delay any kind of memorial service. The date and location will be announced in due course. Letchworth-Sykes Funeral Service in Scotland Neck is handling the arrangements for the Shearin family and online condolences can be directed to the family by visiting letchworthsykesfs.com.
hometownsource.com

Benefit set for Bartkowicz and family

A benefit has been planned for the Rodney Bartkowicz family Saturday, Sept. 25, at 1 p.m. at the Royalton American Legion Post 137. Bartkowicz and his wife, Lynn, grew up in the Little Falls and Upsala/Bowlus areas and call the Bowlus area home. They have three children, Josh, Candace and Zach and four grandchildren.
ROYALTON, MN
malvernobserver.co.uk

NHS launches world first trial for new cancer test

The NHS has this week launched the world’s largest trial of a revolutionary new blood test that can detect more than 50 types of cancer before symptoms appear. The first people to take part will have blood samples taken at mobile testing clinics in retail parks and other convenient community locations.
CANCER
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