#Old World


Manchester United will have to pay £50m for 23-year-old World Cup ace

PSV Eindhoven attacker Cody Gakpo has been linked with a move to the Premier League in recent months. The player was heavily linked with Leeds United in the summer, but he decided to stay at the Dutch club and he has been in fantastic form this season. The 23-year-old had...
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1UPdate: See the first Grammy nominations for best video game score

This February, someone will become the first-ever composer to win the Grammy Award for Best Score Soundtrack for Video Games and Other Interactive Media. This is a new category as of 2023, and it shows just how significant video games have become in the wider lens of culture. The nominees in this category for the 65th Annual Grammy Awards are Aliens: Fire Team Elite by Austin Wintory, Assassin’s Creeed Valhalla: Dawn of Ragnarok by Stephanie Economou, Call of Duty: Vanguard by Bear McCreary, Marvel’s Guardians of the Galaxy by Richard Jacques and Old World by Christopher Tin.
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20-year-old World Cup sensation, Gvardiol: "Real Madrid is the biggest club in the world"

Josko Gvardiol has impressed onlookers at the 2022 World Cup and is now drawing links to Real Madrid. Transfer news and rumours LIVE: Gvardiol addresses Chelsea links | US. Transfer news and rumours LIVE: Gvardiol addresses Chelsea links | US. Bayer Leverkusen are interested in signing Luis Chavez...

Chicken Sausage Soup Italiano has Old World goodness

2 cans 15 ounce great northern beans drained and rinsed. Heat olive oil in large stock pot over medium heat. Add the sliced sausage and cook until crispy brown on both sides remove from the pot and set aside. Add a bit more butter than toss in the diced veggies and cook until just soft. Add the seasonings chicken broth, diced tomatoes, beans. Simmer until done about 15-20 minutes. Add the spinach, sausage, stirring until spinach is wilted sprinkling with the Parmesan cheese. Serve and enjoy!

Brasserie Laurel is Michael Beltran’s Ode to Modern French Cuisine

Chef and restauranteur Michael Beltran has debuted his latest restaurant, Brassierie Laurel a French-focused restaurant in the newly built Miami Worldcenter Caoba residential tower in Downtown Miami. It’s the latest project for his team at Ariete Hospitality Group, whose rapidly growing restaurant portfolio includes Ariete, Nave, Chug’s, and the Taurus...

Holy Creche Nativity Accessory Backdrop Sculpture

$59.99 A stunning Nativity scene can add beauty and inspiration to your Christmas d cor. Now, enhance the reverent charm and serene beauty of your Nativity display with the first-ever Holy Creche Nativity Accessory Sculpture, available exclusively from The Bradford Exchange, Hawthorne Village Division. This Nativity backdrop features buildings and structures faithful to the style of architecture of Bethlehem over 2,000 years ago – serving as the perfect backdrop to evoke the setting of that humble stable in old world Bethlehem.Thorough research went into this heirloom-quality Nativity sculpture to ensure that it would bring that authentic touch of realism to your display with even the tiniest of details. From the roughhewn “wood” of the stable to the coarse texture of the mud bricks to the gentle fronds of the palm trees, each detail is lovingly handcrafted to recreate the city of Bethlehem on that Holy Night. Plus, just behind the crystalline Star of Bethlehem, there’s an opening for insertion of a Christmas light to provide heavenly illumination. Just imagine how glorious your cherished Nativity figurines will look arranged around this truly stunning religious sculpture. Strong demand is expected, so don’t wait. Order now!

With polkas, live reindeer and lots of Krampi, Christkindlmarket Des Moines brings Old World holiday charm to Principal Park

Friday, Dec. 2 and Saturday, Dec. 3, 11 a.m. - 9 p.m.; Sunday, Dec. 4, 11 a.m. - 5 p.m. at Principal Park. The sixth annual Christkindlmarket Des Moines kicked off at Principle Park on Thursday night. The Christmas market, inspired by by the centuries-old European tradition of holiday markets is a celebration of German and Austrian heritage infused with seasonal charm.
France 24

Funny old world: The week's offbeat news

Austrian tourist board bosses pulled a television ad lauding the open-mindedness of the Tyrol region when the local reaction proved the exact opposite. The paean to the beautiful alpine province -- "Come as you are -- in Tyrol everybody is welcome" -- was judged an "affront to Tyrolean farmers" because it featured -- horror of horrors -- the hipster elixir oat milk.

Mower County Sheriff To Take Leave Amid Health, Conduct Concern

Austin, MN (KROC-AM News)- Mower County has retained legal counsel after being advised of a concern regarding Sheriff Steve Sandvick who announced he was temporarily stepping aside to address health issues. A news release from Mower County Administrator Trish Harren says her office was advised on November 17 of a...

Poco Diablo Unveils Willows Kitchen in Time for Holiday Cheer

The Zagat award-winning chef sources seasonal ingredients for the higher-end New American cuisine found on the new Willows Kitchen + Wine Bar menu. Poco Diablo Resort has opened its new restaurant, Willows Kitchen + Wine Bar, as part of a phased $22 million renovation. Although the restaurant had a soft opening Sept. 15, it recently hosted journalists for a preview tasting of the winter menu and pairings with wines from the restaurant’s extensive collection. The tasting showcased Old World and New World wines along with an Arizona white blend.

Freemason Dollar Bill

Freemason Dollar Bill – Many of us do not realize that the symbolism of ancient brotherhood is a part of our daily lives. The Great Seal on the back of the US dollar bill is a symbol used by the Freemasons. Freemasonry began in 1717 in England and in 1770 in Scotland. This Old World government regulated religious discussion. Desperate to break with the past, Freemasons sought ecumenism and religious tolerance. They disagreed with sectarian divisions that led to misunderstandings among many organized religions.

Planet Zoo DLC introduces eight new species

Frontier Developments is expanding the available offerings to zoo owners with the release of the Grasslands Animal Pack. The DLC introduces the Nine-Banded Armadillo, Maned Wolf, Emu, Caracal, Red-Necked Wallaby, Striped Hyena, and Blue Wildebeest. Additionally, the Cloudless Sulphur, European Peacock, Menelaus Blue Morpho, Monarch, and Old World Swallowtail butterflies can be used in the Walkthrough Exhibit.

Centrin-deficient Leishmania mexicana confers protection against Old World visceral leishmaniasis

Leishmaniasis is one of the top neglected tropical diseases with significant morbidity and mortality in low and middle-income countries (LMIC). However, this disease is also spreading in the developed world. Currently, there is a lack of effective strategies to control this disease. Vaccination can be an effective measure to control leishmaniasis and has the potential to achieve disease elimination. Recently, we have generated centrin gene-deleted new world L. mexicana (LmexCen−/−) parasites using CRISPR/Cas9 and showed that they protect mice against a homologous L. mexicana infection that causes cutaneous disease. In this study, we tested whether LmexCen−/− parasites can also protect against visceral leishmaniasis caused by L. donovani in a hamster model. We showed that immunization with LmexCen−/− parasites is safe and does not cause lesions. Furthermore, such immunization conferred protection against visceral leishmaniasis caused by a needle-initiated L. donovani challenge, as indicated by a significant reduction in the parasite burdens in the spleen and liver as well as reduced mortality. Similar control of parasite burden was also observed against a sand fly mediated L. donovani challenge. Importantly, immunization with LmexCen−/− down-regulated the disease promoting cytokines IL-10 and IL-4 and increased pro-inflammatory cytokine IFN-γ resulting in higher IFN-γ/IL-10 and IFN-γ/IL4 ratios compared to non-immunized animals. LmexCen−/− immunization also resulted in long-lasting protection against L. donovani infection. Taken together, our study demonstrates that immunization with LmexCen−/− parasites is safe and efficacious against the Old World visceral leishmaniasis.