The centuries-old Irish brewer Guinness, a unit of Diageo , is set to open a brewery in the Fulton Market district west of Chicago's Loop business district, Crain's Chicago Business reported, citing a developer operating in the fast-evolving area. Formerly home mainly to meatpacking plants, the district has in recent decades been largely overtaken by destination restaurants, boutique hotels, residential conversions and in-fill developments, and most recently corporate flagship office locations, such as those of McDonald's and Google . The brewery and beerhall would likely utilize a disused Pennsylvania Railroad Terminal structure, Crain's reported. According to a Guinness fact sheet, the brewer operates five breweries in five countries around the world while Guinness "is brewed in 49 countries around the world," including licensed locations. A Baltimore brewery that opened in 2017 makes Guinness beers other than the trademark Guinness Extra Stout. Crain's reported that details concerning the planned Chicago site were unknown and that a Guinness representative had declined to comment.