CBS Sports

Fantasy Baseball Today: Shane Baz impresses in debut, Salvador Perez breaks catcher HR record, players to add

Happy Tuesday everyone! Dan Schneier here taking over for Frank for the morning. We're down to the final two weeks of the MLB season and some of you are competing in your championship week matchup for most H2H leagues. For those of you in the Roto scoring formats, every at bat and every pitch still matters. On Monday, we saw the debut of the most dominant minor-league pitcher of the 2021 season, and despite Scott White's previous skepticism, Rays prospect Shane Baz did not disappoint. But more on that below.
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MedPage Today

J&J Says Second Dose of Their COVID Vaccine Boosts Protection

A second dose of Johnson & Johnson's COVID-19 vaccine given 2 months after the standard one-dose regimen was 94% effective against moderate to severe disease in the U.S., the manufacturer said in topline data released on Tuesday. However, the confidence interval was wide, with one case in the vaccine arm...
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Study Finds Inverse Relationship Between OSA, Male Testosterone Levels

An inverse relationship between obstructive sleep apnea (OSA) and serum testosterone was found in men, in which those with severe cases of OSA exhibited significantly reduced levels of testosterone. Incidence and severity of obstructive sleep apnea (OSA) was inversely correlated with male serum testosterone levels, according to study findings published...
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Johnson & Johnson Report Promising COVID-19 Vaccine Booster Efficacy, Long-Term Data

Preprint data from a real-world evidence assessment, as well as preliminary reports from a 2-dose trial, support the company's pursuit for FDA authorization of a second COVID-19 vaccine dose. Johnson & Johnson announced to-be-published phase 3 data from a real-world evidence trial showing their single-dose adenovirus-based COVID-19 vaccine Ad26.COV2.S was...

Improved Outcomes With Trastuzumab Deruxtecan is Associated With HER2 Expression Levels in HER2+ mCRC

In patients with HER2-positive, metastatic colorectal cancer, fam-trastuzumab deruxtecan-nxki led to improved responses in patients with higher HER2 expression at baseline, whereas responses were seen irrespective of RAS- and PIK3CA mutation status and blood tumor mutational burden levels. In patients with HER2-positive, metastatic colorectal cancer (mCRC), fam-trastuzumab deruxtecan-nxki (T-DXd; Enhertu)...

Adavosertib for RAS-/TP53-Mutant Metastatic Colorectal Cancer Reduced Risk of Progression, Death

Adavosertib demonstrated a 65% risk reduction in disease progression and death for patients with TP53-/RAS-mutant metastatic colorectal cancer following first-line chemotherapy. For patients with TP53-/RAS-mutant metastatic colorectal cancer (mCRC) following first-line chemotherapy, adavosertib resulted in a 65% reduction in the risk of disease progression or death when compared with active...

Lasting Response With Sitravatinib Plus Nivolumab Observed After Previous Checkpoint Inhibitors and Chemotherapy For Advanced NSCLC

Patients with advanced non–small cell lung cancer receiving sitravatinib plus nivolumab combination had promising objective responses during a post-hoc analysis of a phase 2 trial. The combination of sitravatinib (Sitra) and nivolumab (Opdivo) as observed in the phase 2 MRTX-500 study (NCT02954991) in patients with advanced non–small cell cancer who...

Netlify Web Development Cloud Now Available in AWS Marketplace

Teams with AWS billing can simplify procurement and use AWS spend commitments for Netlify Enterprise plans. Netlify, the most popular way to build, deploy and scale modern web applications, is now available via the AWS Marketplace, a digital catalog to find, test, buy, and deploy software that runs on Amazon Web Services (AWS). AWS customers can streamline procurement and consolidate web infrastructure billing by purchasing Netlify with their existing AWS account and spending commitments.

Durvalumab/Chemotherapy Combo Demonstrates Durable Survival Benefit in ES-SCLC

Patients with extensive-stage small cell lung cancer (ES-SCLC) derived overall survival benefit from a combination of durvalumab and chemotherapy. A combination of durvalumab (Imfinzi) plus platinum/etoposide chemotherapy has yielded long-term overall survival (OS) benefit vs chemotherapy alone in patients with extensive-stage small cell lung cancer (ES-SCLC), according to findings from the phase 3 CASPIAN trial (NCT03043872), which were presented at the 2021 European Society of Medical Oncology Congress.1.
MedPage Today

Antibody-Drug Conjugate OK'd for Cervical Cancer

The FDA granted accelerated approval to tisotumab vedotin-tftv (Tivdak), a first-in-class drug, for the treatment of patients with recurrent or metastatic cervical cancer, drugmakers Seagen and Genmab announced. Tisotumab vedotin, a tissue factor-directed antibody and microtubule inhibitor conjugate, is indicated for women whose disease progressed on or following chemotherapy. Approval...

Risk of Mortality, Stroke Similar After TAVR for Aortic Stenosis

No significant difference in mortality or stroke at 30 days or 1 year was seen in patients who underwent TAVR for bicuspid or tricuspid aortic stenosis. A recent study evaluated the outcomes of transcatheter aortic valve replacement (TAVR) with contemporary balloon-expandable transcatheter heart valves in bicuspid aortic stenosis versus tricuspid aortic stenosis in patients at low surgical risk.

ShiftLeft CORE on AWS Marketplace

We are pleased to announce that ShiftLeft CORE is now available on the AWS Marketplace! Now, AWS users looking to integrate a complete AppSec platform into their software development lifecycle (SDLC) or CI/CD pipeline have another option for procuring ShiftLeft CORE. Procuring Software via the AWS Marketplace. Over the years,...
IT Business Edge

Top Container Software & Orchestration Tools 2021

In today’s highly competitive technical landscape, testing and development must be performed rapidly yet securely to meet growing consumer demands. When moving software from one computing environment to another, be it from a physical machine in a data center to a virtual machine (VM) in a cloud environment, a staging environment into production or a developer’s laptop to a test environment, the software must run reliably.

How a Dependency Hijacking Vulnerability in Microsoft Teams Highlights Gaps in the Software Supply Chain

The proliferation of third-party software is a boon for developers but introduces gaps in visibility and governance. As a result, the software supply chain has become a prominent attack vector for vulnerable IT systems. Dependency hijacking has gained traction as the latest example of attackers targeting the software supply chain by piggy-backing off of native package managers as a vehicle for malicious code.

Cabometyx Approved for Radioactive Iodine-Refractory Differentiated Thyroid Cancer

The Food and Drug Administration has approved Cabometyx® (cabozantinib) for the treatment of patients 12 years of age and older with locally advanced or metastatic differentiated thyroid cancer that has progressed following prior vascular endothelial growth factor receptor (VEGFR)-targeted therapy and who are radioactive iodine-refractory or ineligible. The approval was...