Chemotherapeutic drugs kill tumor cells and kill healthy cells, which may lead to leukemia, for example. Using platinum-containing chemotherapeutics has been discovered by scientists to induce blood cell mutations in the usual way. Other chemotherapeutic drugs lacked these signs, although there was a strong correlation between treatment duration and therapy-specific alterations in subsequent metastases.
Micronuclei, which are small nucleus-like structures within cells, are commonly associated with tumors. Now, researchers from Tsukuba, Japan have developed an automated computer program that can accurately and reproducibly count these structures from microscope images, which will increase the speed and accuracy of micronuclei research. In a recently published study,...
Breast cancer is a type of cancer that disrupts the function of cell division in breast cells. Breast cancer cells multiply in an infected person, out of control and too much. There are different types of breast cancer. The type depends on which type of breast cell is affected. This cancer can start in different places in the breast.
Scientists at Sloan Kettering discover mRNA inactivates tumor-suppressing proteins, meaning it can promote cancer
There’s a secret layer of information in your cells called messenger RNA, that’s located between DNA and proteins, that serves as a critical link. Now, in a medical shocker to the whole world of vaccine philosophy, scientists at Sloan Kettering found that mRNA itself carries cancer CAUSING changes – changes that genetic tests don’t even analyze, flying completely under the radar of oncologists across the globe.
The DNA in our cells can accumulate damage over may years. Environmental influences like UV light or cigarette smoke may exacerbate the problem, but since cells have to replicate the genome every time they divide (and some cells divide many times thoughout a lifetime), it's been thought that genetic mutations naturally happen as we age. When those mutations occur in genes that suppress the growth of tumors, or keep cell division under control, cancer can happen. But now, researchers have found that many cancer-linked genes are actively involved in suppressing the immune response to cancer. Genes that have previously been associated with cancer may be playing a different role in influencing the development of disease than we knew.
Rogue cells in the bone marrow crowd out healthy cells and leave people vulnerable to infections. Most of the time, multiple myeloma lurks quietly until it's discovered during routine lab work, although sometimes people may experience bone pain, fatigue, or other signs of trouble. In either case, a diagnosis of...
In a new study from the University of Texas, researchers clarified the long-established connection between inflammation and pancreatic cancer development. They found pancreatic cells display an adaptive response to repeated inflammatory episodes that initially protects against tissue damage but can promote tumor formation in the presence of mutant KRAS. The...
Results of 2 studies presented at 2021 ESMO demonstrate superior efficacy of sintilimab plus chemotherapy versus chemotherapy alone in certain gastrointestinal cancers. The addition of sintilimab (Tyvyt) to chemotherapy in patients with unresectable, locally advanced, recurrent, or metastatic esophageal squamous cell carcinoma (ESCC) or unresectable, locally advanced, recurrent, or metastatic gastric or gastroesophageal junction (GEJ) adenocarcinoma was able to improve overall survival (OS) versus chemotherapy alone, according to results of 2 studies that were presented during the 2021 European Society for Medical Oncology Congress.1,2.
Blink-182 singer and bassist Mark Hoppus is grateful to be done with chemotherapy and is awaiting a scan later this month to see how it combated his cancer.
LAREDO, TX. (KGNS) - When it comes to cancer, no battle is easy to handle. At such a young age, Desiree continues fighting for more than a year now and even though it’s been a tough ride, the journey to defeating cancer continues. At just ten years old, Desiree Muniz...
Hokkaido University scientists and colleagues in Japan have found a way that could help some patients overcome resistance to an immunotherapy treatment for cancer. The approach, proven in mice experiments, was reported in the Journal for ImmunoTherapy of Cancer. The activation of checkpoint proteins on the surfaces of immune cells...
Washington [US], September 18 (ANI): A new discovery from researchers at The University of Texas MD Anderson Cancer Center has clarified the long-established connection between inflammation and pancreatic cancer development. The findings of the study were published in the journal 'Science'. According to the study, pancreatic cells display an adaptive...
‘Post-vaccine, what we are seeing is a drop in your killer T-cells, in your CD8 cells,” said Dr. Ryan Cole. A doctor has found an increase in cancers since the COVID-19 inoculation rollout. On March 18, Dr. Ryan Cole, a board-certified pathologist and owner and operator of a diagnostics lab,...
A team of researchers with biotechnology corporation Genentech Inc., has developed a new way to capture the origins and early adaptive processes that are involved in therapy responses to cancer treatments. In their paper published in the journal Nature Biotechnology, the group describes how their new system can be used to help treat resistant types of cancer.
Genetic Engineering News
Tumors use unexpected tricks to evade the immune system, according to new findings from researchers at the Brigham and Women’s Hospital in Boston. The team found that hundreds of cancer-linked genes play an unexpected role in causing disease than previously thought. Tumor suppressor genes (TSGs) have long been known to block cell growth, preventing cancerous cells from spreading. Mutations in these genes, scientists believed, allow tumors to flourish unchecked. This new research shows that more than 100 mutated TSGs can prevent the immune system from spotting and destroying malignant cells in mice.