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Senescent cells—those that have lost the ability to divide—accumulate with age and are key drivers of age-related diseases, such as cancer, dementia and cardiovascular disease. In a new study, a team led by University of Pittsburgh and UPMC Hillman Cancer Center researchers has uncovered a mechanism by which senescent, or "zombie," cells develop.

PITTSBURGH (KDKA) — The Supreme Court's decision to overturn abortion rights for all has created concern about other rights grounded in the same provisions of the U.S. Constitution.As KDKA political editor Jon Delano, an attorney, explains, it's not clear yet how far this conservative court will go in future cases.In law school, hours are spent debating constitutional rights that we often take for granted but are not explicitly spelled out in the Constitution. Now, scholars say the Supreme Court's action in the Dobbs case to overturn abortion rights calls some of those other rights into question."People should be quite concerned...

Mitch Trubisky is turning into a cat with nine lives as he appears to be emerging as the frontrunner to start the 2022 season for the Pittsburgh Steelers. According to Steelers insider Mark Kaboly, rookie first-round pick Kenny Pickett has been working exclusively with the third-string offense in OTAs and minicamps so far. Kaboly believes that only an injury or a terrible training camp will keep him from starting in Week 1.

Sheetz is offering $3.99 gas for a limited time.

PITTSBURGH (KDKA) — Allegheny County and Pittsburgh police are investigating multiple shootings over the weekend.Police say three women were shot on South 12th Street on the South Side after a fight broke out on Saturday morning. Two of the women were shot in the leg and the third woman was shot in the hand.The violence only continued from there, ending with 10 people shot over a three-day period."It's very senseless," Pittsburgh resident Keona Robinson said Monday.The violence started Friday afternoon in the Hill District on Chauncey Drive. One man died and two men were taken in for questioning after a...

PITTSBURGH — Sheetz will be looking to lower some pain at the pump by lowering some of its gas prices on select gas. Unleaded 88 will cost $3.99 a gallon and E85 will cost $3.49 a gallon, effective immediately. Unleaded 88 is approved by the EPA for use in...

You've got to love a Cam Heyward and Mike Tomlin moment.

It doesn't look like Kenny Pickett will be the Pittsburgh Steelers starting quarterback to start the 2022-23 season. Pickett worked exclusively with the third-team offense during OTAs and minicamp, per Mark Kaboly of The Athletic. Mitch Trubisky likely worked with the starters during those sessions and has been seen as...

Evgeni Malkin and Kris Letang are among the biggest names slated to become unrestricted free agents on July 13. There appears to be little progress in contract talks between the Pittsburgh Penguins and their long-time stars. Malkin seems the most likely to depart. The Athletic's Josh Yohe reported the two...

From heartfelt moments to big time performances, Wednesday’s Major League Baseball action was full of great moments. Pittsburgh’s Bryan Reynolds hit three home runs yesterday against the Nationals and Shohei Ohtani’s dominant outing pushed his scoreless innings streak over 21 innings. There’s a lot of drama surrounding Freddie Freeman, his now former agent, and his signing in Los Angeles, but that hasn’t affected his on field performance of late, as he has the longest active hit streak in the majors at 13 games.

The Pittsburgh Steelers find themselves a secondary star in an early 2023 mock draft.

Kevin and Donnie preview the NL Central battle set for Thursday night between the Milwaukee Brewers and Pittsburgh Pirates among a light slate of MLB action.

In this edition of NHL Quick Hits, I’ll look at some news emerging from around the NHL. This news includes Nazem Kadri, Kris Letang, and a host of skating wounded from the Lighting. Quick Hit One: Where Will Nazem Kadri Sign?. The Colorado Avalanche just won the Stanley Cup,...

PITTSBURGH (KDKA) — Sheetz has lowered its price for unleaded 88 gasoline to $3.99 a gallon through the Fourth of July holiday.  Sheetz announced in a release Monday that it is lowering its prices to "reduce pain at the pump for consumers" effective immediately. Sheetz added that is selling E85 gasoline for $3.49 a gallon.  "Unleaded 88 is approved by the EPA for use in vehicles for model years 2001 or newer as well as light-duty trucks, SUVs and Flex Fuel Vehicles," Sheetz said in a release. "E85 contains more ethanol (51%-83%) and is not compatible with all vehicles. It...

The Pittsburgh Steelers need to fill seven snaps per game.

The Pittsburgh Steelers will have a quarterback battle in training camp, but they appear to be giving a strong hint in OTAs about who will win the starting job. Free agent addition Mitchell Trubisky is the heavy favorite to start for the Steelers barring injury or an awful camp, according to Mark Caboly of The Athletic. Rookie Kenny Pickett is not a factor at the moment, and only received third-string reps during OTAs and minicamp.

PITTSBURGH (KDKA) - Mission of Mercy Pittsburgh is requesting the public's help for their upcoming health clinic at the David L. Lawrence Convention Center. The event is scheduled to take place on August 5 and 6, 2022. The organization is looking for more than 1,000 volunteers to assist with the clinic.

Seven weeks after a toddler was found unresponsive in a Munhall home, the boy’s parents have been charged in his death. Robert Kraft died May 13 at UPMC Children’s Hospital. The two-year-old died as a result of a fentanyl overdose, according to Allegheny County police. The medical examiner has ruled his death a homicide.

Tips from the public helped state police identify three men who they believe were involved with the theft of 34 catalytic converters worth $50,000 from vehicles at a Salem RV dealer in October, according to court papers. Troopers said several people reported recognizing Kenneth L. Knight Jr., 43, of Jeannette,...

Prepare to see several unfamiliar faces on local newscasts in the next month as stations restock their on-air ranks. The most notable on-air addition is the arrival this week of WTAE’s new weekday anchor, who will sit alongside Mike Clark during the 11 p.m. newscast. With or without the...