UPDATE (4:30pm): All southbound lanes of Interstate 5 have reopened from Exit 14 in Ashland to the California border, ODOT reported.

The closure began earlier Tuesday due to severe winter conditions in northern California.

"Drivers should expect winter weather conditions and delays as backed up traffic begins moving again," ODOT said.

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Original report:

The Oregon Department of Transportation reports that all southbound lanes of Interstate 5 are closed from Exit 14 in Ashland to the California border due to severe winter conditions in northern California.

Caltrans has closed I-5 northbound from Redding to the Oregon border.

The I-5 Oregon closure, at Caltrans' request, may be long until conditions in California improve.

OR 66 and OR 273 are closed to all but local traffic.

Do not attempt a detour using lesser maintained routes such as Dead Indian Memorial Rd. or Colestin Rd. Trucks: please keep Ashland St. clear if waiting out closure. More Info Here